| pubmed-article:16254824 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16254824 | lifeskim:mentions | umls-concept:C1058973 | lld:lifeskim |
| pubmed-article:16254824 | lifeskim:mentions | umls-concept:C0204727 | lld:lifeskim |
| pubmed-article:16254824 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:16254824 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:16254824 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:16254824 | lifeskim:mentions | umls-concept:C0021838 | lld:lifeskim |
| pubmed-article:16254824 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:16254824 | pubmed:dateCreated | 2005-10-28 | lld:pubmed |
| pubmed-article:16254824 | pubmed:abstractText | A bioassay-guided separation of a methanolic extract obtained from the roots of Boerhaavia diffusa L. (Nyctaginaceae) allowed us to isolate five compounds belonging to the class of rotenoids: the known boeravinone D ( 1), boeravinone E ( 2), compound 5 and two novel compounds that we have named boeravinone G ( 3) and boeravinone H ( 4). The structures of the new molecules have been determined on the basis of their HR-EI-MS, (1)H- and (13)C-NMR and 2D-NMR (HMQC, HMBC) data. All the isolated rotenoids have been evaluated for their effect on intestinal motility in vitro. Three of them (boeravinone G, boeravinone E and compound 5) exhibited spasmolytic activity. Preliminary structure-activity relationships have been established highlighting the effect of substitutions on rings B and D. | lld:pubmed |
| pubmed-article:16254824 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16254824 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16254824 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16254824 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16254824 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16254824 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16254824 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:16254824 | pubmed:issn | 0032-0943 | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:IzzoAngelo... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:BorrelliFranc... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:CapassoFrance... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:CapassoRaffae... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:FattorussoErn... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:Taglialatela-... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:PetrucciFranc... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:MilicNatasaN | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:AscioneValeri... | lld:pubmed |
| pubmed-article:16254824 | pubmed:author | pubmed-author:ValenteRobert... | lld:pubmed |
| pubmed-article:16254824 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16254824 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:16254824 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16254824 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16254824 | pubmed:pagination | 928-32 | lld:pubmed |
| pubmed-article:16254824 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:meshHeading | pubmed-meshheading:16254824... | lld:pubmed |
| pubmed-article:16254824 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16254824 | pubmed:articleTitle | Isolation of new rotenoids from Boerhaavia diffusa and evaluation of their effect on intestinal motility. | lld:pubmed |
| pubmed-article:16254824 | pubmed:affiliation | Dipartimento di Farmacologia Sperimentale, Università di Napoli Federico II, Via D. Montesano 49, 80131 Naples, Italy. franborr@unina.it | lld:pubmed |
| pubmed-article:16254824 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16254824 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16254824 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16254824 | lld:pubmed |
