| pubmed-article:16244707 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16244707 | lifeskim:mentions | umls-concept:C0034865 | lld:lifeskim |
| pubmed-article:16244707 | lifeskim:mentions | umls-concept:C0017428 | lld:lifeskim |
| pubmed-article:16244707 | lifeskim:mentions | umls-concept:C1522609 | lld:lifeskim |
| pubmed-article:16244707 | lifeskim:mentions | umls-concept:C1554112 | lld:lifeskim |
| pubmed-article:16244707 | lifeskim:mentions | umls-concept:C1707494 | lld:lifeskim |
| pubmed-article:16244707 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:16244707 | pubmed:dateCreated | 2006-2-7 | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:abstractText | Genetic recombination is a fundamental evolutionary mechanism promoting biological adaptation. Using engineered recombinants of the small single-stranded DNA plant virus, Maize streak virus (MSV), we experimentally demonstrate that fragments of genetic material only function optimally if they reside within genomes similar to those in which they evolved. The degree of similarity necessary for optimal functionality is correlated with the complexity of intragenomic interaction networks within which genome fragments must function. There is a striking correlation between our experimental results and the types of MSV recombinants that are detectable in nature, indicating that obligatory maintenance of intragenome interaction networks strongly constrains the evolutionary value of recombination for this virus and probably for genomes in general. | lld:pubmed |
| pubmed-article:16244707 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16244707 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16244707 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16244707 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16244707 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:16244707 | pubmed:issn | 1553-7404 | lld:pubmed |
| pubmed-article:16244707 | pubmed:author | pubmed-author:PosadaDavidD | lld:pubmed |
| pubmed-article:16244707 | pubmed:author | pubmed-author:RybickiEdward... | lld:pubmed |
| pubmed-article:16244707 | pubmed:author | pubmed-author:MartinDarren... | lld:pubmed |
| pubmed-article:16244707 | pubmed:author | pubmed-author:van der... | lld:pubmed |
| pubmed-article:16244707 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16244707 | pubmed:volume | 1 | lld:pubmed |
| pubmed-article:16244707 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16244707 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16244707 | pubmed:pagination | e51 | lld:pubmed |
| pubmed-article:16244707 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:meshHeading | pubmed-meshheading:16244707... | lld:pubmed |
| pubmed-article:16244707 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16244707 | pubmed:articleTitle | The evolutionary value of recombination is constrained by genome modularity. | lld:pubmed |
| pubmed-article:16244707 | pubmed:affiliation | Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa. darren@science.uct.ac.za | lld:pubmed |
| pubmed-article:16244707 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16244707 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16244707 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16244707 | lld:pubmed |
