| pubmed-article:16220918 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16220918 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:16220918 | lifeskim:mentions | umls-concept:C0220908 | lld:lifeskim |
| pubmed-article:16220918 | lifeskim:mentions | umls-concept:C0010423 | lld:lifeskim |
| pubmed-article:16220918 | lifeskim:mentions | umls-concept:C1257867 | lld:lifeskim |
| pubmed-article:16220918 | lifeskim:mentions | umls-concept:C0600596 | lld:lifeskim |
| pubmed-article:16220918 | lifeskim:mentions | umls-concept:C0348080 | lld:lifeskim |
| pubmed-article:16220918 | pubmed:issue | 37 | lld:pubmed |
| pubmed-article:16220918 | pubmed:dateCreated | 2005-10-13 | lld:pubmed |
| pubmed-article:16220918 | pubmed:abstractText | Protein crystallization is a major bottleneck in determining tertiary protein structures from genomic sequence data. This paper describes a microfluidic system for screening hundreds of protein crystallization conditions using less than 4 nL of protein solution for each crystallization droplet. The droplets are formed by mixing protein, precipitant, and additive stock solutions in variable ratios in a flow of water-immiscible fluids inside microchannels. Each droplet represents a discrete trial testing different conditions. The system has been validated by crystallization of several water-soluble proteins. | lld:pubmed |
| pubmed-article:16220918 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16220918 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16220918 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16220918 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16220918 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16220918 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16220918 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16220918 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16220918 | pubmed:issn | 0002-7863 | lld:pubmed |
| pubmed-article:16220918 | pubmed:author | pubmed-author:ZhengBoB | lld:pubmed |
| pubmed-article:16220918 | pubmed:author | pubmed-author:IsmagilovRust... | lld:pubmed |
| pubmed-article:16220918 | pubmed:author | pubmed-author:RoachL... | lld:pubmed |
| pubmed-article:16220918 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16220918 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:16220918 | pubmed:volume | 125 | lld:pubmed |
| pubmed-article:16220918 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16220918 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16220918 | pubmed:pagination | 11170-1 | lld:pubmed |
| pubmed-article:16220918 | pubmed:dateRevised | 2008-1-17 | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:meshHeading | pubmed-meshheading:16220918... | lld:pubmed |
| pubmed-article:16220918 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:16220918 | pubmed:articleTitle | Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets. | lld:pubmed |
| pubmed-article:16220918 | pubmed:affiliation | Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA. | lld:pubmed |
| pubmed-article:16220918 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16220918 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:16220918 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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