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pubmed-article:16201357pubmed:abstractTextA substituted 3H-indole quaternary ammonium molecule was designed and synthesized using hexamethylphosphoramide (HMPA) as a solvent. The products were purified and characterized by IR, 1H-NMR, MS and elemental analysis. The binding reaction of this compound with bovine serum albumin (BSA) in aqueous solution was studied using fluorescence. Their binding constant is Ka = 1.995 x 10(5) dm3 x mol(-1) and the binding site number is n = 1.12. It is confirmed that the combination is a single static quenching process.lld:pubmed
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pubmed-article:16201357pubmed:articleTitle[Synthesis of substituted 3H-indole quaternary ammonium salt and study on its interaction with bovine serum albumin by fluorescence].lld:pubmed
pubmed-article:16201357pubmed:affiliationCollege of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.lld:pubmed
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