16137794

Source:http://linkedlifedata.com/resource/pubmed/id/16137794

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Subject	Predicate	Object	Context
pubmed-article:16137794	rdf:type	pubmed:Citation	lld:pubmed
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0439849	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0234238	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0527316	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0220781	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0220825	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C1883254	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0445223	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0243077	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C1552599	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C1704787	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C0205460	lld:lifeskim
pubmed-article:16137794	lifeskim:mentions	umls-concept:C1258007	lld:lifeskim
pubmed-article:16137794	pubmed:issue	12	lld:pubmed
pubmed-article:16137794	pubmed:dateCreated	2005-11-18	lld:pubmed
pubmed-article:16137794	pubmed:abstractText	Sixty-four new indanones and thiaindanones related to donepezil were synthesized and evaluated in vitro as potential AChE inhibitors. Among them, 11 derivatives were found to inhibit the enzyme in the submicromolar range; the best compound revealed its inhibitory activity with an IC50 in the same range (0.06 microM) than the reference compound, donepezil (IC50=0.02 microM).	lld:pubmed
pubmed-article:16137794	pubmed:language	eng	lld:pubmed
pubmed-article:16137794	pubmed:journal	http://linkedlifedata.com/r...	lld:pubmed
pubmed-article:16137794	pubmed:citationSubset	IM	lld:pubmed
pubmed-article:16137794	pubmed:chemical	http://linkedlifedata.com/r...	lld:pubmed
pubmed-article:16137794	pubmed:chemical	http://linkedlifedata.com/r...	lld:pubmed
pubmed-article:16137794	pubmed:chemical	http://linkedlifedata.com/r...	lld:pubmed
pubmed-article:16137794	pubmed:chemical	http://linkedlifedata.com/r...	lld:pubmed
pubmed-article:16137794	pubmed:status	MEDLINE	lld:pubmed
pubmed-article:16137794	pubmed:month	Dec	lld:pubmed
pubmed-article:16137794	pubmed:issn	0223-5234	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:DallemagnePat...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:RaultSylvainS	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:Le...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:DauphinFranço...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:LisowskiVince...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:BoulouardMich...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:FabisFrédéric...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:LescotElodieE	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:SantosJana...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:OmranZiadZ	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:CaillyThomasT	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:AgondanouJean...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:GodardAnne-Ma...	lld:pubmed
pubmed-article:16137794	pubmed:author	pubmed-author:StiebingSilvi...	lld:pubmed
pubmed-article:16137794	pubmed:issnType	Print	lld:pubmed
pubmed-article:16137794	pubmed:volume	40	lld:pubmed
pubmed-article:16137794	pubmed:owner	NLM	lld:pubmed
pubmed-article:16137794	pubmed:authorsComplete	Y	lld:pubmed
pubmed-article:16137794	pubmed:pagination	1222-45	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:meshHeading	pubmed-meshheading:16137794...	lld:pubmed
pubmed-article:16137794	pubmed:year	2005	lld:pubmed
pubmed-article:16137794	pubmed:articleTitle	Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil.	lld:pubmed
pubmed-article:16137794	pubmed:affiliation	Centre d'études et de recherche sur le médicament de Normandie, département de pharmacochimie U.F.R. des sciences pharmaceutiques, université de Caen Basse-Normandie, boulevard Becquerel, 14032 Caen cedex, France.	lld:pubmed
pubmed-article:16137794	pubmed:publicationType	Journal Article	lld:pubmed