| pubmed-article:16133447 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16133447 | lifeskim:mentions | umls-concept:C1708431 | lld:lifeskim |
| pubmed-article:16133447 | lifeskim:mentions | umls-concept:C0262950 | lld:lifeskim |
| pubmed-article:16133447 | lifeskim:mentions | umls-concept:C0007570 | lld:lifeskim |
| pubmed-article:16133447 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:16133447 | lifeskim:mentions | umls-concept:C1517488 | lld:lifeskim |
| pubmed-article:16133447 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:16133447 | pubmed:dateCreated | 2005-10-5 | lld:pubmed |
| pubmed-article:16133447 | pubmed:abstractText | Celiac disease (CD) is associated with decreased bone mineral mass. Its pathogenesis is multifactorial since both systemic and local mechanisms may play a role. Our objective was to determine whether single-nucleotide polymorphisms in genes encoding members of the interleukin-1 family are associated with bone damage measured by densitometry in a series of 71 adult CD patients assessed at diagnosis. When compared with non-carrier CD patients, carriers of allele T of the interleukin-1beta gene (IL1B-511T) had a significantly lower bone mass at the total skeleton level (p = 0.0484) and a greater prevalence of osteopenia/osteoporosis (p = 0.0102). To our knowledge, this is the first evidence on the association between a genetic predisposition and low bone mass in CD patients. This finding supports the postulated inflammation-associated bone loss pathogenesis as one of the causes of bone weakness in CD. | lld:pubmed |
| pubmed-article:16133447 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16133447 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16133447 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16133447 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16133447 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16133447 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16133447 | pubmed:issn | 0093-7711 | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:PeñaA SAS | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:LimP GPG | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:MorenoM LML | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:SugaiEE | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:SambuelliAA | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:MauriñoEE | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:CherñavskyAA | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:VazquezHH | lld:pubmed |
| pubmed-article:16133447 | pubmed:author | pubmed-author:CrusiusJ B... | lld:pubmed |
| pubmed-article:16133447 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16133447 | pubmed:volume | 57 | lld:pubmed |
| pubmed-article:16133447 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16133447 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16133447 | pubmed:pagination | 618-20 | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:meshHeading | pubmed-meshheading:16133447... | lld:pubmed |
| pubmed-article:16133447 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16133447 | pubmed:articleTitle | The IL-1 gene family and bone involvement in celiac disease. | lld:pubmed |
| pubmed-article:16133447 | pubmed:affiliation | Department of Medicine, C. Bonorino Udaondo Gastroenterology Hospital, Buenos Aires, Argentina. | lld:pubmed |
| pubmed-article:16133447 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:3553 | entrezgene:pubmed | pubmed-article:16133447 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:16133447 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16133447 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16133447 | lld:pubmed |
