pubmed-article:15996212 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15996212 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
pubmed-article:15996212 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
pubmed-article:15996212 | lifeskim:mentions | umls-concept:C0003591 | lld:lifeskim |
pubmed-article:15996212 | lifeskim:mentions | umls-concept:C0043096 | lld:lifeskim |
pubmed-article:15996212 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
pubmed-article:15996212 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
pubmed-article:15996212 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:15996212 | pubmed:dateCreated | 2005-7-5 | lld:pubmed |
pubmed-article:15996212 | pubmed:abstractText | Apolipoprotein A5 is a recently discovered apolipoprotein involved primarily in triglyceride metabolism. Several single-nucleotide polymorphisms have been investigated since the initial report. The -1131T>C polymorphism has been associated with higher triglyceride levels and a decreased high-density lipoprotein cholesterol as well as with susceptibility to coronary heart disease. However, no study has so far emphasized on the association of a dietary intervention with apolipoprotein A5 polymorphisms. In a group of 606 hyperlipaemic and overweight men, we investigated how a short-term fat restriction affects lipid traits and body mass index (BMI) in wildtype and carriers of the -1131T>C polymorphism. Our result was that the reduction of BMI was significantly higher in C allele carriers (p=0.0021). Since the -1131T>C polymorphism predisposes to coronary heart disease, a restriction diet is an important therapeutic approach in -1131T>C carriers. | lld:pubmed |
pubmed-article:15996212 | pubmed:language | eng | lld:pubmed |
pubmed-article:15996212 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15996212 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:15996212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15996212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:15996212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15996212 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15996212 | pubmed:month | Aug | lld:pubmed |
pubmed-article:15996212 | pubmed:issn | 0009-9163 | lld:pubmed |
pubmed-article:15996212 | pubmed:author | pubmed-author:EvansDD | lld:pubmed |
pubmed-article:15996212 | pubmed:author | pubmed-author:BeilF UFU | lld:pubmed |
pubmed-article:15996212 | pubmed:author | pubmed-author:SeedorfUU | lld:pubmed |
pubmed-article:15996212 | pubmed:author | pubmed-author:AberleJJ | lld:pubmed |
pubmed-article:15996212 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15996212 | pubmed:volume | 68 | lld:pubmed |
pubmed-article:15996212 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15996212 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15996212 | pubmed:pagination | 152-4 | lld:pubmed |
pubmed-article:15996212 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:15996212 | pubmed:year | 2005 | lld:pubmed |
pubmed-article:15996212 | pubmed:articleTitle | A polymorphism in the apolipoprotein A5 gene is associated with weight loss after short-term diet. | lld:pubmed |
pubmed-article:15996212 | pubmed:affiliation | Zentrum für Innere Medizin, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany. aberle@uke.uni-hamburg.de | lld:pubmed |
pubmed-article:15996212 | pubmed:publicationType | Journal Article | lld:pubmed |
entrez-gene:116519 | entrezgene:pubmed | pubmed-article:15996212 | lld:entrezgene |
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