pubmed-article:15914848 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15914848 | lifeskim:mentions | umls-concept:C0038975 | lld:lifeskim |
pubmed-article:15914848 | lifeskim:mentions | umls-concept:C1325725 | lld:lifeskim |
pubmed-article:15914848 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:15914848 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
pubmed-article:15914848 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
pubmed-article:15914848 | lifeskim:mentions | umls-concept:C0033105 | lld:lifeskim |
pubmed-article:15914848 | lifeskim:mentions | umls-concept:C0205360 | lld:lifeskim |
pubmed-article:15914848 | pubmed:issue | Pt 6 | lld:pubmed |
pubmed-article:15914848 | pubmed:dateCreated | 2005-5-25 | lld:pubmed |
pubmed-article:15914848 | pubmed:abstractText | Possible human infection with simian virus 40 (SV40) has been of great concern ever since SV40 was discovered in polio vaccines. Human populations are SV40-seropositive, but because of serological cross-reactivity between SV40 and the human polyomaviruses BK virus (BKV) and JC virus (JCV), it is debatable whether these antibodies are specific. An SV40-specific serological assay was established, based on purified virus-like particles (VLPs), where the SV40 VLPs were blocked with hyperimmune sera to BKV and JCV. Competition with SV40 hyperimmune sera was used as a confirmatory test. Among 288 Swedish children of between 1 and 13 years of age, 7.6 % had SV40-specific antibodies. SV40 seroprevalence reached a peak of 14 % at 7-9 years of age. Among 100 control patients with benign tumours, 9 % were SV40-seropositive. However, SV40 DNA was not detectable in corresponding buffy-coat samples. In serial samples taken up to 5 years apart from 141 Finnish women participating in the population-based serological screening for congenital infections, only two of 141 women were SV40-seropositive in both samples. Six women seroconverted and eight women had a loss of antibodies over time. None of the SV40-seropositive samples contained detectable SV40 DNA. In conclusion, there is a low prevalence of SV40-specific antibodies in the Nordic population. The SV40 antibodies appear to have a low stability over time and their origin is not clear. | lld:pubmed |
pubmed-article:15914848 | pubmed:language | eng | lld:pubmed |
pubmed-article:15914848 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15914848 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:15914848 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15914848 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15914848 | pubmed:month | Jun | lld:pubmed |
pubmed-article:15914848 | pubmed:issn | 0022-1317 | lld:pubmed |
pubmed-article:15914848 | pubmed:author | pubmed-author:SasnauskasKes... | lld:pubmed |
pubmed-article:15914848 | pubmed:author | pubmed-author:LehtinenMatti... | lld:pubmed |
pubmed-article:15914848 | pubmed:author | pubmed-author:DillnerJoakim... | lld:pubmed |
pubmed-article:15914848 | pubmed:author | pubmed-author:KoskelaPentti... | lld:pubmed |
pubmed-article:15914848 | pubmed:author | pubmed-author:EliassonLinda... | lld:pubmed |
pubmed-article:15914848 | pubmed:author | pubmed-author:LundstigAnnik... | lld:pubmed |
pubmed-article:15914848 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15914848 | pubmed:volume | 86 | lld:pubmed |
pubmed-article:15914848 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15914848 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15914848 | pubmed:pagination | 1703-8 | lld:pubmed |
pubmed-article:15914848 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:15914848 | pubmed:meshHeading | pubmed-meshheading:15914848... | lld:pubmed |
pubmed-article:15914848 | pubmed:year | 2005 | lld:pubmed |
pubmed-article:15914848 | pubmed:articleTitle | Prevalence and stability of human serum antibodies to simian virus 40 VP1 virus-like particles. | lld:pubmed |
pubmed-article:15914848 | pubmed:affiliation | Department of Medical Microbiology, Malmö University Hospital, Entrance 78, 20502 Malmö, Sweden. | lld:pubmed |
pubmed-article:15914848 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:15914848 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:15914848 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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