| pubmed-article:15863270 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15863270 | lifeskim:mentions | umls-concept:C0376358 | lld:lifeskim |
| pubmed-article:15863270 | lifeskim:mentions | umls-concept:C0919437 | lld:lifeskim |
| pubmed-article:15863270 | lifeskim:mentions | umls-concept:C0599155 | lld:lifeskim |
| pubmed-article:15863270 | lifeskim:mentions | umls-concept:C1422480 | lld:lifeskim |
| pubmed-article:15863270 | lifeskim:mentions | umls-concept:C1514468 | lld:lifeskim |
| pubmed-article:15863270 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:15863270 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:15863270 | pubmed:dateCreated | 2005-5-2 | lld:pubmed |
| pubmed-article:15863270 | pubmed:abstractText | The candidate prostate cancer gene ELAC2 encodes tRNA 3' processing endoribonuclease (tRNase ZL). We produced recombinant human tRNase ZL's, which contain one to three amino-acid substitutions from three missense mutations (Ser217Leu, Ala541Thr, and Arg781His) that are associated with the occurrence of prostate cancer. These enzymes were examined for the pre-tRNA cleavage and the RNase 65 activity. We did not observe any differences in enzymatic properties such as Km and k(cat) values between the wild-type tRNase ZL and its variants. We conclude that there is no causality between the enzymatic properties of tRNase ZL and the prostate cancer. | lld:pubmed |
| pubmed-article:15863270 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15863270 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15863270 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15863270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15863270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15863270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15863270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15863270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15863270 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15863270 | pubmed:month | May | lld:pubmed |
| pubmed-article:15863270 | pubmed:issn | 0304-3835 | lld:pubmed |
| pubmed-article:15863270 | pubmed:author | pubmed-author:TakagiMasamic... | lld:pubmed |
| pubmed-article:15863270 | pubmed:author | pubmed-author:TakakuHiroaki... | lld:pubmed |
| pubmed-article:15863270 | pubmed:author | pubmed-author:NashimotoMasa... | lld:pubmed |
| pubmed-article:15863270 | pubmed:author | pubmed-author:MinagawaAsako... | lld:pubmed |
| pubmed-article:15863270 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15863270 | pubmed:day | 26 | lld:pubmed |
| pubmed-article:15863270 | pubmed:volume | 222 | lld:pubmed |
| pubmed-article:15863270 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15863270 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15863270 | pubmed:pagination | 211-5 | lld:pubmed |
| pubmed-article:15863270 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:meshHeading | pubmed-meshheading:15863270... | lld:pubmed |
| pubmed-article:15863270 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15863270 | pubmed:articleTitle | The missense mutations in the candidate prostate cancer gene ELAC2 do not alter enzymatic properties of its product. | lld:pubmed |
| pubmed-article:15863270 | pubmed:affiliation | Department of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niitsu, Niigata 956-8603, Japan. | lld:pubmed |
| pubmed-article:15863270 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15863270 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15863270 | lld:pubmed |
