| pubmed-article:15843082 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15843082 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:15843082 | lifeskim:mentions | umls-concept:C0010346 | lld:lifeskim |
| pubmed-article:15843082 | lifeskim:mentions | umls-concept:C0085295 | lld:lifeskim |
| pubmed-article:15843082 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:15843082 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:15843082 | lifeskim:mentions | umls-concept:C0013331 | lld:lifeskim |
| pubmed-article:15843082 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:15843082 | pubmed:dateCreated | 2005-4-21 | lld:pubmed |
| pubmed-article:15843082 | pubmed:abstractText | Interleukin-10 is an anti-inflammatory and immunomodulatory cytokine. Interleukin-10 deficient mice are prone to develop chronic colitis. Administration of recombinant human interleukin-10 has been proposed to have a beneficial effect in a subgroup of patients with Crohn's disease. Recently, we found an interleukin-10 Gly15Arg mutation in a family with Crohn's disease which is associated with reduced interleukin-10 secretion by in vitro stimulated monocytes and lymphocytes. We hypothesised that this interleukin-10 mutation plays a role in maintaining the inflammatory process in Crohn's disease in some families. | lld:pubmed |
| pubmed-article:15843082 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15843082 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15843082 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15843082 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15843082 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15843082 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15843082 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15843082 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15843082 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15843082 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15843082 | pubmed:month | May | lld:pubmed |
| pubmed-article:15843082 | pubmed:issn | 1590-8658 | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:KuipersE JEJ | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:van der... | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:de JongD JDJ | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:WilsonJ H PJH | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:CrusiusJ B... | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:de RooijF W... | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:NaberT H JTH | lld:pubmed |
| pubmed-article:15843082 | pubmed:author | pubmed-author:BoorP P CPP | lld:pubmed |
| pubmed-article:15843082 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15843082 | pubmed:volume | 37 | lld:pubmed |
| pubmed-article:15843082 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15843082 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15843082 | pubmed:pagination | 330-5 | lld:pubmed |
| pubmed-article:15843082 | pubmed:dateRevised | 2008-5-13 | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:meshHeading | pubmed-meshheading:15843082... | lld:pubmed |
| pubmed-article:15843082 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15843082 | pubmed:articleTitle | A functional interleukin-10 mutation in Dutch patients with Crohn's disease. | lld:pubmed |
| pubmed-article:15843082 | pubmed:affiliation | Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands. | lld:pubmed |
| pubmed-article:15843082 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15843082 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:15843082 | pubmed:publicationType | Multicenter Study | lld:pubmed |
| entrez-gene:3586 | entrezgene:pubmed | pubmed-article:15843082 | lld:entrezgene |
| entrez-gene:64127 | entrezgene:pubmed | pubmed-article:15843082 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15843082 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15843082 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:15843082 | lld:entrezgene |
