| pubmed-article:15805381 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C0021294 | lld:lifeskim |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C0034656 | lld:lifeskim |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C1704437 | lld:lifeskim |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C0771648 | lld:lifeskim |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:15805381 | lifeskim:mentions | umls-concept:C1609686 | lld:lifeskim |
| pubmed-article:15805381 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15805381 | pubmed:dateCreated | 2005-4-4 | lld:pubmed |
| pubmed-article:15805381 | pubmed:abstractText | Available therapeutic surfactants are either animal-derived or non-protein-containing synthetic products. Animal-derived surfactants contain variable amounts of surfactant apoproteins, whereas the older-generation synthetic products contain only phospholipids and lack surfactant proteins (SPs). Both decrease morbidity and mortality rates associated with respiratory distress syndrome (RDS) among preterm infants, compared with placebo. However, excess mortality rates have been observed with non-protein-containing synthetic surfactants, compared with the animal-derived products. Evidence suggests that synthetic surfactants consisting solely of phospholipids can be improved with the addition of peptides that are functional analogs of SPs. Lucinactant is a new synthetic peptide-containing surfactant that contains sinapultide, a novel, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human SP-B. It is completely devoid of animal-derived components. | lld:pubmed |
| pubmed-article:15805381 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15805381 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15805381 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15805381 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:15805381 | pubmed:issn | 1098-4275 | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:MassaroJoseph... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:GadzinowskiJa... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:WiswellThomas... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:BernsteinGrah... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:Lacaze-Masmon... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:SinhaSunil... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:SegalRobertR | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:Sanchez-LunaM... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:AytacogluBarl... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:SchaberChrist... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:d'AgostinoRal... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:Valls i... | lld:pubmed |
| pubmed-article:15805381 | pubmed:author | pubmed-author:HajduJuliaJ | lld:pubmed |
| pubmed-article:15805381 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:15805381 | pubmed:volume | 115 | lld:pubmed |
| pubmed-article:15805381 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15805381 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15805381 | pubmed:pagination | 1030-8 | lld:pubmed |
| pubmed-article:15805381 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:meshHeading | pubmed-meshheading:15805381... | lld:pubmed |
| pubmed-article:15805381 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15805381 | pubmed:articleTitle | A multicenter, randomized, controlled trial of lucinactant versus poractant alfa among very premature infants at high risk for respiratory distress syndrome. | lld:pubmed |
| pubmed-article:15805381 | pubmed:affiliation | Department of Paediatrics and Neonatal Medicine, University of Durham and James Cook University Hospital, Middlesbrough, United Kingdom. sunil.sinha@stees.nhs.uk | lld:pubmed |
| pubmed-article:15805381 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15805381 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:15805381 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:15805381 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:15805381 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:15805381 | pubmed:publicationType | Multicenter Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15805381 | lld:pubmed |
