| pubmed-article:15797730 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C0084378 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C0444626 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C1883221 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C1883204 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C1880389 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C0052850 | lld:lifeskim |
| pubmed-article:15797730 | lifeskim:mentions | umls-concept:C0997935 | lld:lifeskim |
| pubmed-article:15797730 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:15797730 | pubmed:dateCreated | 2005-3-30 | lld:pubmed |
| pubmed-article:15797730 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15797730 | pubmed:abstractText | The Dugesia japonica vasa-like gene B (DjVLGB) protein is a DEAD-box RNA helicase of a planarian, which is well known for its strong regenerative capacity. DjVLGB shares sequence similarity to the Drosophila germ-line-specific DEAD-box RNA helicase Vasa, and even higher similarity to its paralogue, mouse PL10. In this study, we solved the crystal structure of the DjVLGB N-terminal RecA-like domain. The overall fold and the structures of the putative ATPase active site of the DjVLGB N-terminal RecA-like domain are similar to those of the previously reported DEAD-box RNA helicase structures. In contrast, the surface structure of the side opposite to the putative ATPase active site is different from those of the other DEAD-box RNA helicases; the characteristic hydrophobic pockets are formed with aromatic and proline residues. These pocket-forming residues are conserved in the PL10-subfamily proteins, but less conserved in the Vasa orthologues and not conserved in the DEAD-box RNA helicases. Therefore, the structural features that we found are characteristic of the PL10-subfamily proteins and might contribute to their biological roles in germ-line development. | lld:pubmed |
| pubmed-article:15797730 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15797730 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15797730 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15797730 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15797730 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15797730 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15797730 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15797730 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15797730 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:15797730 | pubmed:issn | 1047-8477 | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:AgataKiyokazu... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:YabukiTakashi... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:KigawaTakanor... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:YokoyamaShige... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:OkumuraHiromi... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:ShirouzuMikak... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:TanakaAkikoA | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:TeradaTakahoT | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:MutoYutakaY | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:MatsudaTakayo... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:KashikawaMaki... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:ShibataNorito... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:AokiMasaakiM | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:SekiEikoE | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:ObayashiNaomi... | lld:pubmed |
| pubmed-article:15797730 | pubmed:author | pubmed-author:KurimotoKazuk... | lld:pubmed |
| pubmed-article:15797730 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15797730 | pubmed:volume | 150 | lld:pubmed |
| pubmed-article:15797730 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15797730 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15797730 | pubmed:pagination | 58-68 | lld:pubmed |
| pubmed-article:15797730 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:meshHeading | pubmed-meshheading:15797730... | lld:pubmed |
| pubmed-article:15797730 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15797730 | pubmed:articleTitle | Crystal structure of the N-terminal RecA-like domain of a DEAD-box RNA helicase, the Dugesia japonica vasa-like gene B protein. | lld:pubmed |
| pubmed-article:15797730 | pubmed:affiliation | RIKEN Genomic Sciences Center, Tsurumi, Yokohama 230-0045, Japan. | lld:pubmed |
| pubmed-article:15797730 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15797730 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15797730 | lld:pubmed |
