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pubmed-article:15716695pubmed:abstractTextIn both humans and rats, polymorphisms of the alpha adducin (ADD1) gene are involved in renal sodium handling, essential hypertension and some of its organ complications. Adducin functions within cells as a heterodimer composed of various combinations of three subunits that are coded by three genes (ADD1, 2, 3) each located on a different chromosome.lld:pubmed
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pubmed-article:15716695pubmed:articleTitleRole of the adducin family genes in human essential hypertension.lld:pubmed
pubmed-article:15716695pubmed:affiliationDivision of Nephrology, Dialysis and Hypertension University Vita-Salute, IRCCS San Raffaele Hospital, Milano, Italy. lanzani.chiara@hsr.itlld:pubmed
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