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pubmed-article:1562609pubmed:abstractTextTo identify important structural features in the intergenic sequences of ribosomal DNAs, the nucleotide sequence of the 18-25S rRNA intergenic region was determined in a thermophilic alga, Cyanidium caldarium. Although the mature 5.8S RNA is more stable to thermal denaturation, sequence comparisons reveal a longer molecule with a surprisingly low G/C nucleotide composition. Estimates of the structure further indicate that, unlike other thermophilic examples, thermostability in this organism results, at least in part, from an extended secondary structure.lld:pubmed
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pubmed-article:1562609pubmed:articleTitleExtended secondary structure as a basis of increased RNA stability in a thermophilic alga Cyanidium caldarium.lld:pubmed
pubmed-article:1562609pubmed:affiliationDepartment of Molecular Biology and Genetics, University of Guelph, Canada.lld:pubmed
pubmed-article:1562609pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1562609pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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