pubmed-article:15616297 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C0314787 | lld:lifeskim |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C0006968 | lld:lifeskim |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
pubmed-article:15616297 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:15616297 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:15616297 | pubmed:dateCreated | 2004-12-23 | lld:pubmed |
pubmed-article:15616297 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15616297 | pubmed:abstractText | A carbapenem-resistant Acinetobacter baumannii strain was isolated in Toulouse, France, in 2003. Cloning and expression in Escherichia coli identified the carbapenem-hydrolyzing beta-lactamase OXA-58, which is weakly related (less than 50% amino acid identity) to other oxacillinases. It hydrolyzed penicillins, oxacillin, and imipenem but not expanded-spectrum cephalosporins. The bla(OXA-58) gene was located on a ca. 30-kb non-self-transferable plasmid. After electrotransformation in the A. baumannii CIP7010(T) reference strain, it conferred reduced susceptibility to carbapenems. The bla(OXA-58) gene was bracketed by two novel ISAba3-like insertion elements. This study describes a newly characterized beta-lactamase that may contribute to carbapenem resistance in A. baumannii. | lld:pubmed |
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pubmed-article:15616297 | pubmed:language | eng | lld:pubmed |
pubmed-article:15616297 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15616297 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:15616297 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15616297 | pubmed:month | Jan | lld:pubmed |
pubmed-article:15616297 | pubmed:issn | 0066-4804 | lld:pubmed |
pubmed-article:15616297 | pubmed:author | pubmed-author:PoirelLaurent... | lld:pubmed |
pubmed-article:15616297 | pubmed:author | pubmed-author:NordmannPatri... | lld:pubmed |
pubmed-article:15616297 | pubmed:author | pubmed-author:HéritierClair... | lld:pubmed |
pubmed-article:15616297 | pubmed:author | pubmed-author:ChabanonGérar... | lld:pubmed |
pubmed-article:15616297 | pubmed:author | pubmed-author:SegondsChrist... | lld:pubmed |
pubmed-article:15616297 | pubmed:author | pubmed-author:MarquéSophieS | lld:pubmed |
pubmed-article:15616297 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15616297 | pubmed:volume | 49 | lld:pubmed |
pubmed-article:15616297 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15616297 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15616297 | pubmed:pagination | 202-8 | lld:pubmed |
pubmed-article:15616297 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:15616297 | pubmed:year | 2005 | lld:pubmed |
pubmed-article:15616297 | pubmed:articleTitle | OXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. | lld:pubmed |
pubmed-article:15616297 | pubmed:affiliation | Service de Bactériologie-Virologie, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre Cedex, France. | lld:pubmed |
pubmed-article:15616297 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:15616297 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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