| pubmed-article:15581620 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C0010453 | lld:lifeskim |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C0004112 | lld:lifeskim |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C0041904 | lld:lifeskim |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C0030012 | lld:lifeskim |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C1441290 | lld:lifeskim |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
| pubmed-article:15581620 | lifeskim:mentions | umls-concept:C1515926 | lld:lifeskim |
| pubmed-article:15581620 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:15581620 | pubmed:dateCreated | 2004-12-7 | lld:pubmed |
| pubmed-article:15581620 | pubmed:abstractText | The aim of this study was to evaluate the involvement of oxidative stress in glutamate-evoked transglutaminase (TGase) upregulation in astrocyte cultures (14 DIV). A 24 h exposure to glutamate caused a dose-dependent depletion of glutathione intracellular content and increased the ROS production in cell cultures. These effects were receptor-mediated, as demonstrated by inhibition with GYKI 52466. The pre-incubation with glutathione ethyl ester or cysteamine recovered oxidative status and was effective in significantly reducing glutamate-increased tissue TGase. These data suggest that tissue TGase upregulation may be part of a biochemical response to oxidative stress induced by a prolonged exposure of astrocyte cultures to glutamate. | lld:pubmed |
| pubmed-article:15581620 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15581620 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15581620 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15581620 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15581620 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:15581620 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15581620 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15581620 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:15581620 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:ParisiGG | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:AvolaRR | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:IentileRR | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:VanellaAA | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:CampisiAA | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:CaccamoDD | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:Li VoltiGG | lld:pubmed |
| pubmed-article:15581620 | pubmed:author | pubmed-author:CurròMM | lld:pubmed |
| pubmed-article:15581620 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15581620 | pubmed:day | 3 | lld:pubmed |
| pubmed-article:15581620 | pubmed:volume | 578 | lld:pubmed |
| pubmed-article:15581620 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15581620 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15581620 | pubmed:pagination | 80-4 | lld:pubmed |
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| pubmed-article:15581620 | pubmed:meshHeading | pubmed-meshheading:15581620... | lld:pubmed |
| pubmed-article:15581620 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15581620 | pubmed:articleTitle | Glutamate-evoked redox state alterations are involved in tissue transglutaminase upregulation in primary astrocyte cultures. | lld:pubmed |
| pubmed-article:15581620 | pubmed:affiliation | Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, V.le A. Doria, 6, 95100 Catania, Italy. | lld:pubmed |
| pubmed-article:15581620 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:56083 | entrezgene:pubmed | pubmed-article:15581620 | lld:entrezgene |
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