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pubmed-article:15514523pubmed:abstractTextActivated factor VIIa (FVIIa) was developed to treat hemophiliacs with high-titer antibodies to factor VIII. FVIIa initiates thrombin formation by binding with exposed tissue factor. Anecdotal reports have described the utility of FVIIa in correcting coagulopathy from trauma, but no large series exists. We present our experience with 81 coagulopathic trauma patients treated using FVIIa in years 2001-2003, compared with "control" patients matched from the trauma registry from the same time period.lld:pubmed
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pubmed-article:15514523pubmed:articleTitleFactor VIIa for correction of traumatic coagulopathy.lld:pubmed
pubmed-article:15514523pubmed:affiliationProgram in Trauma, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. rdutton@umaryland.edulld:pubmed
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