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pubmed-article:15381202pubmed:abstractTextA major problem facing islet transplantation is immune destruction of grafts by transplant rejection and autoimmunity. Some success in prolonging graft rejection has been obtained by transducing islets prior to transplantation with adenoviral (Ad) vectors containing CTLA4-Ig and TGFbeta. The purpose of this study was to see if lentiviral (LV) vectors would provide superior results compared with adenoviral vectors.lld:pubmed
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pubmed-article:15381202pubmed:articleTitleTransplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectors.lld:pubmed
pubmed-article:15381202pubmed:affiliationSection on Islet Transplantation and Cell Biology, Joslin Diabetes Center, Harvard Medical School, One Joslin Place, Room 535, Boston, MA 02215, USA.lld:pubmed
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