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pubmed-article:15380780pubmed:abstractTextProtective immunity against cutaneous leishmaniasis is dependent on the induction of Th1/Tc1 immune responses resulting in efficient parasite elimination. In this review, the mechanisms leading to protection are discussed with special focus on the role of Leishmania major-infected dendritic cells (DC) in induction of Th1-dependent immunity. Murine strain-dependent differences between DC derived from Leishmania-susceptible as compared to resistant mice are highlighted.lld:pubmed
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pubmed-article:15380780pubmed:articleTitleRequirements for Th1-dependent immunity against infection with Leishmania major.lld:pubmed
pubmed-article:15380780pubmed:affiliationDepartment of Dermatology, Johannes Gutenberg-University, Langenbeckstrasse 1, D-55101 Mainz, Germany. vonstebu@mail.uni-mainz.delld:pubmed
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