| pubmed-article:15363126 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0023467 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C1512310 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0376515 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C1332823 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0001515 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0382569 | lld:lifeskim |
| pubmed-article:15363126 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:15363126 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:15363126 | pubmed:dateCreated | 2004-9-14 | lld:pubmed |
| pubmed-article:15363126 | pubmed:abstractText | To study the importance of chemokine SDF-1 in surviving of acute myelocytic leukemia cells HL-60, the adhesion ability of HL-60 and expression of Bcl-2, Fas protein when SDF-1 activity was blocked by anti-CXCR4 monoclonal antibody (12G5) were compared with those detected before MAb incubation, in this experiment, HL-60 cell were cultured and co-cultured with normal marrow stromal cell. The adhesion rate was detected while the expression of Bcl-2 and Fas proteins were assayed by immunohistochemical technique when SDF-1 activity was inhibited. The results showed that cell adhesion rate of HL-60 decreased while the expression Bcl-2 decreased and Fas increased. It is concluded that inhibition of SDF-1 activity increases cell apoptosis and thus reduces life-span of leukemia cell at certain level. | lld:pubmed |
| pubmed-article:15363126 | pubmed:language | chi | lld:pubmed |
| pubmed-article:15363126 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15363126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15363126 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15363126 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:15363126 | pubmed:issn | 1009-2137 | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:FuY PYP | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:AHH | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:HongLiuL | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:ZhangYiY | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:ChengChangC | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:KongPei-YanPY | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:ChenXing-HuaX... | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:PengXian-GuiX... | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:ZengDong-Feng... | lld:pubmed |
| pubmed-article:15363126 | pubmed:author | pubmed-author:WangQing-YuQY | lld:pubmed |
| pubmed-article:15363126 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15363126 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:15363126 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15363126 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15363126 | pubmed:pagination | 436-40 | lld:pubmed |
| pubmed-article:15363126 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:meshHeading | pubmed-meshheading:15363126... | lld:pubmed |
| pubmed-article:15363126 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15363126 | pubmed:articleTitle | [Effects of anti- CXCR4 monoclonal antibody on adhesiveness of human acute myelocytic leukemia cell line HL-60 and expression of Bcl-2, Fas proteins]. | lld:pubmed |
| pubmed-article:15363126 | pubmed:affiliation | Department of Hematology, Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, China. | lld:pubmed |
| pubmed-article:15363126 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15363126 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:15363126 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
