| pubmed-article:152801 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:152801 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:152801 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:152801 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:152801 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:152801 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:152801 | lifeskim:mentions | umls-concept:C0443288 | lld:lifeskim |
| pubmed-article:152801 | lifeskim:mentions | umls-concept:C1511636 | lld:lifeskim |
| pubmed-article:152801 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:152801 | pubmed:dateCreated | 1979-2-23 | lld:pubmed |
| pubmed-article:152801 | pubmed:abstractText | Cross-reactive T-cell cytotoxicity is seen when cytotoxic responses are generated in mixed lymphocyte cultures either between mouse strans which differ at the major histocompatibility complex, H-2, or between H-2b mutant strains and the strain from which they were derived. This cross-reactivity can be measured with [51Cr] labeled target cells from a number of different H-2 haplotypes, and the pattern of cross-reaction indicates that the target antigens are unlikely to be any of the serologically defined public specificities. In contrast, the specificity of H-2 restricted cytotoxic responses, such as that to the male-specific antigen, H-Y, is exquisite, and male cells from strains of mice carrying H-2 haplotypes other than the responder have never been found to act as appropriate targets. The contrast between the specificity of anti-H-2 and H-2 restricted responses may argue for a greater idiotypic homogeneity of the cells makiing H-2 restricted responses, and the greater specificity of these responses may be necessary for their biological function. | lld:pubmed |
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| pubmed-article:152801 | pubmed:language | eng | lld:pubmed |
| pubmed-article:152801 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:152801 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:152801 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:152801 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:152801 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:152801 | pubmed:author | pubmed-author:SimpsonEE | lld:pubmed |
| pubmed-article:152801 | pubmed:author | pubmed-author:BaileyDD | lld:pubmed |
| pubmed-article:152801 | pubmed:author | pubmed-author:ChandlerPP | lld:pubmed |
| pubmed-article:152801 | pubmed:author | pubmed-author:HurmeMM | lld:pubmed |
| pubmed-article:152801 | pubmed:author | pubmed-author:BrunnerCC | lld:pubmed |
| pubmed-article:152801 | pubmed:author | pubmed-author:HetheringtonC... | lld:pubmed |
| pubmed-article:152801 | pubmed:author | pubmed-author:MobraatenLL | lld:pubmed |
| pubmed-article:152801 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:152801 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:152801 | pubmed:volume | 148 | lld:pubmed |
| pubmed-article:152801 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:152801 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:152801 | pubmed:pagination | 1478-87 | lld:pubmed |
| pubmed-article:152801 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:152801 | pubmed:year | 1978 | lld:pubmed |
| pubmed-article:152801 | pubmed:articleTitle | Cross-reactive cytotoxic responses. H-2 restricted are more specific than anti-H-2 responses. | lld:pubmed |
| pubmed-article:152801 | pubmed:publicationType | Journal Article | lld:pubmed |
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