| pubmed-article:15203153 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0034830 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0014898 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C1260969 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C1554963 | lld:lifeskim |
| pubmed-article:15203153 | lifeskim:mentions | umls-concept:C0066393 | lld:lifeskim |
| pubmed-article:15203153 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:15203153 | pubmed:dateCreated | 2004-6-18 | lld:pubmed |
| pubmed-article:15203153 | pubmed:abstractText | The development of novel agents for the differentiation of neuronal nicotinic acetylcholine receptors (nAChRs) is important for the treatment of a variety of pathological conditions. We have prepared and evaluated a number of simpler analogues of the norditerpeniod alkaloid methyllycaconitine (MLA) in an effort to understand molecular determinants of nAChR*small molecule interactions. We have previously reported the synthesis and evaluation of a series of ring E analogues of MLA. We report here the optimization of the alpha3beta4* functional activity of this series of compounds through modification of the ester. | lld:pubmed |
| pubmed-article:15203153 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15203153 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15203153 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15203153 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:15203153 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:15203153 | pubmed:author | pubmed-author:BryantDarrell... | lld:pubmed |
| pubmed-article:15203153 | pubmed:author | pubmed-author:McKayDennis... | lld:pubmed |
| pubmed-article:15203153 | pubmed:author | pubmed-author:IsmailKhadiga... | lld:pubmed |
| pubmed-article:15203153 | pubmed:author | pubmed-author:BergmeierStep... | lld:pubmed |
| pubmed-article:15203153 | pubmed:author | pubmed-author:McKaySusanS | lld:pubmed |
| pubmed-article:15203153 | pubmed:author | pubmed-author:ArasonKristja... | lld:pubmed |
| pubmed-article:15203153 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15203153 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:15203153 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:15203153 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15203153 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15203153 | pubmed:pagination | 3739-42 | lld:pubmed |
| pubmed-article:15203153 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:meshHeading | pubmed-meshheading:15203153... | lld:pubmed |
| pubmed-article:15203153 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15203153 | pubmed:articleTitle | Structure activity studies of ring E analogues of methyllycaconitine. Part 2: Synthesis of antagonists to the alpha3beta4* nicotinic acetylcholine receptors through modifications to the ester. | lld:pubmed |
| pubmed-article:15203153 | pubmed:affiliation | Department of Chemistry and Biochemistry, Ohio University, Athens, OH 45701, USA. bergmeis@ohio.edu | lld:pubmed |
| pubmed-article:15203153 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15203153 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15203153 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15203153 | lld:chembl |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15203153 | lld:pubmed |
