| pubmed-article:15187521 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0043552 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0039082 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0071349 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C1418269 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C1999216 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0392756 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:15187521 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:15187521 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:15187521 | pubmed:dateCreated | 2004-6-9 | lld:pubmed |
| pubmed-article:15187521 | pubmed:abstractText | Poly(ADP-ribose) is synthesized from nicotinamide adenine dinucleotide by poly(ADP-ribose) polymerase (PARP) and degraded by poly(ADP-ribose) glycohydrolase (PARG). The activation of the PARP/PARG pathway has been found in a variety of animal models of diseases, including septic shock-like syndrome. We have previously demonstrated that PARP inhibition by 3-ami-nobenzamide or GPI 6150 ameliorates multiple organ dysfunctions induced by zymosan. In the present study, we investigated whether similar effect could be achieved through PARG inhibition to break the cycle of poly(ADP-ribose) turnaround. | lld:pubmed |
| pubmed-article:15187521 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15187521 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15187521 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15187521 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15187521 | pubmed:issn | 0090-3493 | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:ZhangJieJ | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:CaputiAchille... | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:CuzzocreaSalv... | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:LiJia-HeJH | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:Di... | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:GenoveseTizia... | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:MassudaEdmond... | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:XuWeizhengW | lld:pubmed |
| pubmed-article:15187521 | pubmed:author | pubmed-author:CatalanoPaolo... | lld:pubmed |
| pubmed-article:15187521 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15187521 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:15187521 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15187521 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15187521 | pubmed:pagination | 1365-74 | lld:pubmed |
| pubmed-article:15187521 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:15187521 | pubmed:meshHeading | pubmed-meshheading:15187521... | lld:pubmed |
| pubmed-article:15187521 | pubmed:meshHeading | pubmed-meshheading:15187521... | lld:pubmed |
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| pubmed-article:15187521 | pubmed:meshHeading | pubmed-meshheading:15187521... | lld:pubmed |
| pubmed-article:15187521 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15187521 | pubmed:articleTitle | Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice. | lld:pubmed |
| pubmed-article:15187521 | pubmed:affiliation | Department of Clinical and Experimental Medicine and Pharmacology, Torre Biologica, Policlinico Universitario, Messina, Italy. | lld:pubmed |
| pubmed-article:15187521 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15187521 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15187521 | lld:pubmed |
