| pubmed-article:15161769 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0152035 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0012655 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0011860 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0019907 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0008633 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0750484 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0034606 | lld:lifeskim |
| pubmed-article:15161769 | lifeskim:mentions | umls-concept:C0441633 | lld:lifeskim |
| pubmed-article:15161769 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:15161769 | pubmed:dateCreated | 2004-5-26 | lld:pubmed |
| pubmed-article:15161769 | pubmed:abstractText | We conducted an autosomal genome scan to map loci for type 2 diabetes in a Hong Kong Chinese population. We studied 64 families, segregating type 2 diabetes, of which 57 had at least one member with an age at diagnosis of </=40 years. These families included a total of 126 affected sibpairs and 4 other affected relative pairs. Nonparametric linkage analysis revealed seven regions showing nominal evidence for linkage with type 2 diabetes (logarithm of odds [LOD] >0.59, P(pointwise) < 0.05): chromosome 1 at 173.9 cM (LOD = 3.09), chromosome 3 at 26.3 cM (LOD = 1.27), chromosome 4 at 135.3 cM (LOD = 2.63), chromosome 5 at 139.3 cM (LOD = 0.84), chromosome 6 at 178.9 cM (LOD = 1.91), chromosome 12 at 48.7 cM (LOD = 1.99), and chromosome 18 at 28.1 cM (LOD = 1.00). Simulation studies showed genome-wide significant evidence for linkage of the chromosome 1 region (P(genome-wide) = 0.036). We have confirmed the results of previous studies for the presence of a susceptibility locus on chromosome 1q21-q25 (173.9 cM) and suggest the locations of other loci that may contribute to the development of type 2 diabetes in Hong Kong Chinese. | lld:pubmed |
| pubmed-article:15161769 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15161769 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15161769 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15161769 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15161769 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15161769 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:15161769 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15161769 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15161769 | pubmed:issn | 0012-1797 | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:CoxNancy JNJ | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:BellGraeme... | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:CockramClive... | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:ChanJuliana... | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:CritchleyJuli... | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:NgMaggie C... | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:SoWing-YeeWY | lld:pubmed |
| pubmed-article:15161769 | pubmed:author | pubmed-author:LamVincent... | lld:pubmed |
| pubmed-article:15161769 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15161769 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:15161769 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15161769 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15161769 | pubmed:pagination | 1609-13 | lld:pubmed |
| pubmed-article:15161769 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:15161769 | pubmed:meshHeading | pubmed-meshheading:15161769... | lld:pubmed |
| pubmed-article:15161769 | pubmed:meshHeading | pubmed-meshheading:15161769... | lld:pubmed |
| pubmed-article:15161769 | pubmed:meshHeading | pubmed-meshheading:15161769... | lld:pubmed |
| pubmed-article:15161769 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15161769 | pubmed:articleTitle | Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25. | lld:pubmed |
| pubmed-article:15161769 | pubmed:affiliation | Howard Hughes Medical Institute, University of Chicago, 5841 S. Maryland Ave., MC1028, Chicago, IL 60637, USA. maggieng@uchicago.edu | lld:pubmed |
| pubmed-article:15161769 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15161769 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15161769 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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