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pubmed-article:15118174pubmed:abstractTextFractalkine (FKN), a chemokine expressed by inflamed endothelium, induces leukocyte adhesion and migration via the receptor CX3CR1. The polymorphisms V249I and T280M affect receptor expression and function. The role of FKN in atherosclerosis has been recently demonstrated. The aim of this study was to investigate a possible association between CX3CR1 polymorphisms and increased risk of internal carotid artery (ICA) occlusive disease.lld:pubmed
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pubmed-article:15118174pubmed:articleTitleInternal carotid artery occlusive disease and polymorphisms of fractalkine receptor CX3CR1: a genetic risk factor.lld:pubmed
pubmed-article:15118174pubmed:affiliationDipartimento MCO, Clinica Chirurgica Generale, Università degli Studi di Milano, Polo S. Paolo, Milano, Italia. giorgio.ghilardi@unimi.itlld:pubmed
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