Combination chemotherapy with continuous 5-fluorouracil (5-FU) and cisplatin in a monthly regimen is one of the standard treatments for advanced gastric carcinoma. This study evaluated the new LV5FU2-P regimen, designed to improve efficacy and tolerance of the 5-FU plus cisplatin combination.
Combination of folinic acid, 5-fluorouracil bolus and infusion, and cisplatin (LV5FU2-P regimen) in patients with advanced gastric or gastroesophageal junction carcinoma.
Hepato-Gastroenterology and Digestive Oncology, CHU Ambroise Paré, 9 Avenue Charles de Gaulle, AP-HP, F-92100 Boulogne-Billancourt, France. emmanuel.mitry@apr.ap-hop-paris.fr