| pubmed-article:1503439 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1503439 | lifeskim:mentions | umls-concept:C0032276 | lld:lifeskim |
| pubmed-article:1503439 | lifeskim:mentions | umls-concept:C0005050 | lld:lifeskim |
| pubmed-article:1503439 | lifeskim:mentions | umls-concept:C0018270 | lld:lifeskim |
| pubmed-article:1503439 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:1503439 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1503439 | pubmed:dateCreated | 1992-9-16 | lld:pubmed |
| pubmed-article:1503439 | pubmed:abstractText | Nine antimicrotubule benzimidazole derivatives tested in a Pneumocystis carinii culture system with human embryonic lung fibroblast monolayers inhibited organism proliferation. The concentrations of drugs inhibitory in culture ranged from 10 to 0.1 micrograms/ml, with thiabendazole being the least effective (10 micrograms/ml) and parbendazole being the most effective (0.1 microgram/ml). The parent compound, benzimidazole, was inactive at 10 micrograms/ml. Demonstration that this group of compounds has activity against P. carinii provides a new potential target that can be exploited, the microtubules. Also, the variability in the effectiveness of the compounds provides the basis for studies of structure-activity relationships, which were initiated in this study. | lld:pubmed |
| pubmed-article:1503439 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1503439 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1503439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1503439 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1503439 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1503439 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:1503439 | pubmed:author | pubmed-author:SmithJ WJW | lld:pubmed |
| pubmed-article:1503439 | pubmed:author | pubmed-author:QueenerS FSF | lld:pubmed |
| pubmed-article:1503439 | pubmed:author | pubmed-author:BartlettM SMS | lld:pubmed |
| pubmed-article:1503439 | pubmed:author | pubmed-author:EdlindT DTD | lld:pubmed |
| pubmed-article:1503439 | pubmed:author | pubmed-author:ShawM MMM | lld:pubmed |
| pubmed-article:1503439 | pubmed:author | pubmed-author:DurkinM MMM | lld:pubmed |
| pubmed-article:1503439 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1503439 | pubmed:volume | 36 | lld:pubmed |
| pubmed-article:1503439 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1503439 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1503439 | pubmed:pagination | 779-82 | lld:pubmed |
| pubmed-article:1503439 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
| pubmed-article:1503439 | pubmed:meshHeading | pubmed-meshheading:1503439-... | lld:pubmed |
| pubmed-article:1503439 | pubmed:meshHeading | pubmed-meshheading:1503439-... | lld:pubmed |
| pubmed-article:1503439 | pubmed:meshHeading | pubmed-meshheading:1503439-... | lld:pubmed |
| pubmed-article:1503439 | pubmed:meshHeading | pubmed-meshheading:1503439-... | lld:pubmed |
| pubmed-article:1503439 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1503439 | pubmed:articleTitle | Antimicrotubule benzimidazoles inhibit in vitro growth of Pneumocystis carinii. | lld:pubmed |
| pubmed-article:1503439 | pubmed:affiliation | Indiana University School of Medicine, Indianapolis 46202-5250. | lld:pubmed |
| pubmed-article:1503439 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1503439 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1503439 | lld:pubmed |
