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pubmed-article:14977990pubmed:abstractTextWe have identified a Crp/Fnr-like transcriptional regulator of Streptococcus pyogenes that when inactivated attenuates virulence. The gene, named srv for streptococcal regulator of virulence, encodes a 240-amino-acid protein with 53% amino acid similarity to PrfA, a transcriptional activator of virulence in Listeria monocytogenes.lld:pubmed
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pubmed-article:14977990pubmed:articleTitleIdentification of srv, a PrfA-like regulator of group A streptococcus that influences virulence.lld:pubmed
pubmed-article:14977990pubmed:affiliationLaboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA. sreid@wfubmc.edulld:pubmed
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