| pubmed-article:1476558 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1476558 | lifeskim:mentions | umls-concept:C0001973 | lld:lifeskim |
| pubmed-article:1476558 | lifeskim:mentions | umls-concept:C1413353 | lld:lifeskim |
| pubmed-article:1476558 | lifeskim:mentions | umls-concept:C0005516 | lld:lifeskim |
| pubmed-article:1476558 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:1476558 | lifeskim:mentions | umls-concept:C1144465 | lld:lifeskim |
| pubmed-article:1476558 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:1476558 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:1476558 | pubmed:dateCreated | 1993-2-11 | lld:pubmed |
| pubmed-article:1476558 | pubmed:abstractText | Plasma cholesteryl ester transfer protein (CETP) activity was measured in 52 alcoholics and 38 controls and compared with conventional laboratory markers of alcoholism. Mean daily alcohol intake was 180 g/day among the alcoholics and 10 g/day among the controls. Plasma CETP activity was 26% lower in the alcoholics (P < 0.001) and was inversely correlated with daily alcohol intake (r = -0.288, P < 0.05). CETP activity detected 63% of the alcoholics, and its specificity was 82% if the cut-off point was set at the mean CETP activity of the controls -1 SD. The mean -2 SD gave a very low sensitivity for CETP (8%) and cannot be used as its cut-off point. The sensitivities and specificities of gamma glutamyltransferase, aspartate aminotransferase, alanine aminotransferase, mean corpuscular volume and high-density lipoprotein cholesterol were similar to those of CETP activity when the cut-off point for CETP was mean -1 SD. The results thus indicate that plasma CETP activity is not sufficient as a single marker of alcoholism but could be used as an additional method to detect alcohol misuse, although its wide variation in normal population and the elaborate analysis limit its usefulness. | lld:pubmed |
| pubmed-article:1476558 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1476558 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1476558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1476558 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1476558 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1476558 | pubmed:issn | 0735-0414 | lld:pubmed |
| pubmed-article:1476558 | pubmed:author | pubmed-author:SavolainenM... | lld:pubmed |
| pubmed-article:1476558 | pubmed:author | pubmed-author:HannukselaMM | lld:pubmed |
| pubmed-article:1476558 | pubmed:author | pubmed-author:KesäniemiY... | lld:pubmed |
| pubmed-article:1476558 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1476558 | pubmed:volume | 27 | lld:pubmed |
| pubmed-article:1476558 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1476558 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1476558 | pubmed:pagination | 557-62 | lld:pubmed |
| pubmed-article:1476558 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:meshHeading | pubmed-meshheading:1476558-... | lld:pubmed |
| pubmed-article:1476558 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1476558 | pubmed:articleTitle | Evaluation of plasma cholesteryl ester transfer protein (CETP) activity as a marker of alcoholism. | lld:pubmed |
| pubmed-article:1476558 | pubmed:affiliation | Department of Internal Medicine, University of Oulu, Finland. | lld:pubmed |
| pubmed-article:1476558 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1476558 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
