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pubmed-article:14675047pubmed:abstractTextHarmful uremic toxins, such as indoxyl sulfate (IS), 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), indoleacetate (IA), and hippurate (HA), accumulate to a high degree in uremic plasma. IS has been shown to be a substrate of rat organic anion transporter 1 (rOat1) and rOat3. However, the contribution of rOat1 and rOat3 to the renal uptake transport process of IS and other uremic toxins in the kidney remains unknown.lld:pubmed
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pubmed-article:14675047pubmed:affiliationGraduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.lld:pubmed
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