| pubmed-article:14644028 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14644028 | lifeskim:mentions | umls-concept:C0007587 | lld:lifeskim |
| pubmed-article:14644028 | lifeskim:mentions | umls-concept:C0815000 | lld:lifeskim |
| pubmed-article:14644028 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:14644028 | pubmed:dateCreated | 2003-12-3 | lld:pubmed |
| pubmed-article:14644028 | pubmed:abstractText | CCR5 is expressed in neurons but its function in this cellular context is hitherto poorly understood. We have generated CCR5-expressing SH-SY5Y neuroblastoma cells. CCR5 ligands induced cell death in these cells, but not in control neuroblastoma cells or in CCR5-expressing fibroblasts. CCR5-dependent killing of neuroblastoma cells occurred through apoptosis, since it was accompanied by caspase-3 activation and could be prevented by a caspase-3 inhibitor. Finally, cell killing by activated microglia was more rapid and extensive in CCR5-expressing neuroblastoma cells than in control cells. In summary, CCR5 may act as a death receptor in cells of neuronal lineage and therefore be involved in inflammatory neurodegeneration. | lld:pubmed |
| pubmed-article:14644028 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14644028 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14644028 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14644028 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14644028 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:14644028 | pubmed:issn | 0165-5728 | lld:pubmed |
| pubmed-article:14644028 | pubmed:author | pubmed-author:Irminger-Fing... | lld:pubmed |
| pubmed-article:14644028 | pubmed:author | pubmed-author:KrauseKarl-He... | lld:pubmed |
| pubmed-article:14644028 | pubmed:author | pubmed-author:HartleyOliver... | lld:pubmed |
| pubmed-article:14644028 | pubmed:author | pubmed-author:Dubois-Dauphi... | lld:pubmed |
| pubmed-article:14644028 | pubmed:author | pubmed-author:CartierLaetit... | lld:pubmed |
| pubmed-article:14644028 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14644028 | pubmed:volume | 145 | lld:pubmed |
| pubmed-article:14644028 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14644028 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14644028 | pubmed:pagination | 27-39 | lld:pubmed |
| pubmed-article:14644028 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
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| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
| pubmed-article:14644028 | pubmed:meshHeading | pubmed-meshheading:14644028... | lld:pubmed |
| pubmed-article:14644028 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:14644028 | pubmed:articleTitle | Chemokine-induced cell death in CCR5-expressing neuroblastoma cells. | lld:pubmed |
| pubmed-article:14644028 | pubmed:affiliation | Biology of Ageing Laboratory, Department of Geriatrics, Geneva University Hospitals, 1225 Chêne-Bourg, Switzerland. | lld:pubmed |
| pubmed-article:14644028 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14644028 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:1234 | entrezgene:pubmed | pubmed-article:14644028 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:14644028 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14644028 | lld:pubmed |
