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pubmed-article:14592588pubmed:abstractTextTo compare a newly developed oxytocin antagonist, FE 200 440, with atosiban and ANTAG III, as to potency and selectivity of inhibitory effects on oxytocin- and vasopressin-induced myometrial responses. FE 200 440 has high affinity for the human cloned oxytocin receptor, approximately 300-fold that for the vasopressin V(1a) receptor, whereas atosiban binds well to both receptors.lld:pubmed
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pubmed-article:14592588pubmed:articleTitleFE 200 440: a selective oxytocin antagonist on the term-pregnant human uterus.lld:pubmed
pubmed-article:14592588pubmed:affiliationDepartment of Obstetrics and Gynecology, Lund University Hospital, Sweden.lld:pubmed
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