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pubmed-article:14559444pubmed:abstractTextDelivery of vascular endothelial growth factor (VEGF) protein or gene transfer has been shown to accelerate re-endothelialization and attenuate neointimal hyperplasia in various arterial injury models, including balloon injury, stent implantation, and vein grafts. In addition to stimulating re-endothelialization, we hypothesize that VEGF has further vascular protective functions to prevent neointimal hyperplasia by directly inhibiting mitogen-induced proliferation of vascular smooth muscle cells (VSMCs) via the mitogen-activated protein kinase pathway.lld:pubmed
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pubmed-article:14559444pubmed:articleTitleVascular endothelial growth factor inhibits mitogen-induced vascular smooth muscle cell proliferation.lld:pubmed
pubmed-article:14559444pubmed:affiliationDivision of Vascular Surgery and UCLA Gonda (Goldschmird) Diabetes Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.lld:pubmed
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