| pubmed-article:1448671 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1448671 | lifeskim:mentions | umls-concept:C0684249 | lld:lifeskim |
| pubmed-article:1448671 | lifeskim:mentions | umls-concept:C0022972 | lld:lifeskim |
| pubmed-article:1448671 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:1448671 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:1448671 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:1448671 | lifeskim:mentions | umls-concept:C0868928 | lld:lifeskim |
| pubmed-article:1448671 | pubmed:issue | 6-7 | lld:pubmed |
| pubmed-article:1448671 | pubmed:dateCreated | 1992-12-29 | lld:pubmed |
| pubmed-article:1448671 | pubmed:abstractText | The clinical and electrophysiological data of 18 consecutive adult patients with paraneoplastic Lambert-Eaton myasthenic syndrome (LMES) have been reviewed. The cancer associated with LEMS was small-cell lung carcinoma (SCLC) in 15 cases and epidermoid lung carcinoma in 3 cases. The main clinical neurological features were proximal lower limb weakness (100%), depressed tendon reflexes (94%) and dryness of the mouth (66%). The results of repetitive nerve stimulation (RNS) were not statistically different in the paraneoplastic LEMS group and in a group of 6 LMS patients in whom no carcinoma had been detected. Low-amplitude compound muscle action potential (CMAP) was present in all cases; decremental response at low stimulation rates was present in 13/15 cases. An abnormal incremental response at high stimulation rates was observed in all cases. A close correlation between CMAP amplitude and clinical condition was found in 4 cases during the long-term follow-up. In one patient the RNS electrical pattern could be misinterpreted as myasthenia gravis in only one muscle tested. We underline the usefulness of a 50 Hz stimulation during 4 seconds to establish the diagnosis unequivocally, and that of post-exercise facilitation in routine detection among an SCLC population. Our results suggest that CAMP amplitude and RNS test could be used to evaluate the short-term improvement of LMS under treatment and, in some cases, for the long-term follow-up. The infraclinical axonal neuropathy detected in 8 patients probably was another associated autoimmune paraneoplastic complication. | lld:pubmed |
| pubmed-article:1448671 | pubmed:language | fre | lld:pubmed |
| pubmed-article:1448671 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1448671 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1448671 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1448671 | pubmed:issn | 0035-3787 | lld:pubmed |
| pubmed-article:1448671 | pubmed:author | pubmed-author:VialCC | lld:pubmed |
| pubmed-article:1448671 | pubmed:author | pubmed-author:BadyBB | lld:pubmed |
| pubmed-article:1448671 | pubmed:author | pubmed-author:ChauplannazGG | lld:pubmed |
| pubmed-article:1448671 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1448671 | pubmed:volume | 148 | lld:pubmed |
| pubmed-article:1448671 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1448671 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1448671 | pubmed:pagination | 513-9 | lld:pubmed |
| pubmed-article:1448671 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:meshHeading | pubmed-meshheading:1448671-... | lld:pubmed |
| pubmed-article:1448671 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1448671 | pubmed:articleTitle | [Lambert-Eaton syndrome: clinical and electrophysiological study of 18 cases associated with lung cancer]. | lld:pubmed |
| pubmed-article:1448671 | pubmed:affiliation | Service d'Electromyographie, Hôpital Neurologique, Lyon. | lld:pubmed |
| pubmed-article:1448671 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1448671 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:1448671 | pubmed:publicationType | Review | lld:pubmed |
