| pubmed-article:1396872 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C0007194 | lld:lifeskim |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C0001128 | lld:lifeskim |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C0019409 | lld:lifeskim |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C0303023 | lld:lifeskim |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C1704711 | lld:lifeskim |
| pubmed-article:1396872 | lifeskim:mentions | umls-concept:C0044870 | lld:lifeskim |
| pubmed-article:1396872 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:1396872 | pubmed:dateCreated | 1992-10-28 | lld:pubmed |
| pubmed-article:1396872 | pubmed:abstractText | IT has been proposed that iodine-123 15-(p-iodophenyl)-3-R,S-methylpentadecanoic acid (123I-BMIPP) is an agent for myocardial fatty acid metabolism in animal models. The aim of the present study was to determine whether alterations in fatty acid uptake and/or utilization in patients with hypertrophic cardiomyopathy (HCM) could be detected by 123I-BMIPP. Myocardial imaging with 123I-BMIPP and thallium-201 (201Tl) was performed in 14 fasted patients. A dose of 111 MBq of 123I-BMIPP was administered intravenously at rest, and myocardial emission computed tomography was obtained 20 min and 3 h after injection. The 201Tl imaging was also performed within 1 week after the 123I-BMIPP study. The regional myocardial uptake and clearance of 123I-BMIPP and 201Tl were assessed quantitatively. The myocardial distribution of 123I-BMIPP was more heterogeneous than that of 201Tl in patients with HCM. The myocardial uptake of 123I-BMIPP was lower in the anteroseptal region of the left ventricle than in the posterolateral region (74% vs. 85%, P less than 0.001). The anteroseptal wall showed a faster clearance of 123I-BMIPP than the posterolateral wall (33% vs. 27%, P less than 0.01). Both a decreased uptake and rapid clearance of 123I-BMIPP were observed in the hypertrophied myocardium of the anteroseptal wall, where 201Tl uptake was normal or even increased. Myocardial segments with a markedly increased thickness showed a lower uptake and faster clearance of 123I-BMIPP than those with mild hypertrophy (uptake 73% vs. 82%, P less than 0.05; clearance 30% vs. 25%, P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:1396872 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1396872 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1396872 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1396872 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1396872 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1396872 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1396872 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1396872 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1396872 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1396872 | pubmed:issn | 0340-6997 | lld:pubmed |
| pubmed-article:1396872 | pubmed:author | pubmed-author:AbeSS | lld:pubmed |
| pubmed-article:1396872 | pubmed:author | pubmed-author:TomoikeHH | lld:pubmed |
| pubmed-article:1396872 | pubmed:author | pubmed-author:ChibaJJ | lld:pubmed |
| pubmed-article:1396872 | pubmed:author | pubmed-author:KomataniAA | lld:pubmed |
| pubmed-article:1396872 | pubmed:author | pubmed-author:TonookaII | lld:pubmed |
| pubmed-article:1396872 | pubmed:author | pubmed-author:TakeishiYY | lld:pubmed |
| pubmed-article:1396872 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1396872 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:1396872 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1396872 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1396872 | pubmed:pagination | 775-82 | lld:pubmed |
| pubmed-article:1396872 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:meshHeading | pubmed-meshheading:1396872-... | lld:pubmed |
| pubmed-article:1396872 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1396872 | pubmed:articleTitle | Heterogeneous myocardial distribution of iodine-123 15-(p-iodophenyl)-3-R,S-methylpentadecanoic acid (BMIPP) in patients with hypertrophic cardiomyopathy. | lld:pubmed |
| pubmed-article:1396872 | pubmed:affiliation | First Department of Internal Medicine, Yamagata University School of Medicine, Japan. | lld:pubmed |
| pubmed-article:1396872 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1396872 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1396872 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1396872 | lld:pubmed |
