pubmed-article:1382106 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C0019682 | lld:lifeskim |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C0229601 | lld:lifeskim |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C0238607 | lld:lifeskim |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C1332710 | lld:lifeskim |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
pubmed-article:1382106 | lifeskim:mentions | umls-concept:C0301625 | lld:lifeskim |
pubmed-article:1382106 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:1382106 | pubmed:dateCreated | 1992-10-22 | lld:pubmed |
pubmed-article:1382106 | pubmed:abstractText | Hematopoietic progenitor (CD34+) cells were purified from the bone marrow of 6 human immunodeficiency virus (HIV) type 1-seropositive cytopenic patients and 10 healthy donors. HIV-1-seropositive patients showed a reduced number of granulocyte/macrophage, erythroid, and megakaryocyte progenitors and also a progressive and significant decline of numbers of CD34+ cells in liquid culture, which did not result from a productive or latent HIV-1 infection of CD34+ cells. However, all HIV-1-seropositive patients showed signs of active viral replication at the bone marrow level. Moreover, virus isolates from 3 HIV-1-seropositive patients showed a dose-dependent inhibition on growth of normal CD34+ cells. This suppressive activity was almost completely reversed by incubating the virus isolates with an anti-gp120 polyclonal antibody before adding to normal CD34+ cells. | lld:pubmed |
pubmed-article:1382106 | pubmed:language | eng | lld:pubmed |
pubmed-article:1382106 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1382106 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:1382106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1382106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1382106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1382106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1382106 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1382106 | pubmed:month | Oct | lld:pubmed |
pubmed-article:1382106 | pubmed:issn | 0022-1899 | lld:pubmed |
pubmed-article:1382106 | pubmed:author | pubmed-author:MazzaPP | lld:pubmed |
pubmed-article:1382106 | pubmed:author | pubmed-author:La PlacaMM | lld:pubmed |
pubmed-article:1382106 | pubmed:author | pubmed-author:ReM CMC | lld:pubmed |
pubmed-article:1382106 | pubmed:author | pubmed-author:VisaniGG | lld:pubmed |
pubmed-article:1382106 | pubmed:author | pubmed-author:FurliniGG | lld:pubmed |
pubmed-article:1382106 | pubmed:author | pubmed-author:ZauliGG | lld:pubmed |
pubmed-article:1382106 | pubmed:author | pubmed-author:VignoliMM | lld:pubmed |
pubmed-article:1382106 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1382106 | pubmed:volume | 166 | lld:pubmed |
pubmed-article:1382106 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1382106 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1382106 | pubmed:pagination | 710-6 | lld:pubmed |
pubmed-article:1382106 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:1382106 | pubmed:year | 1992 | lld:pubmed |
pubmed-article:1382106 | pubmed:articleTitle | Evidence for a human immunodeficiency virus type 1-mediated suppression of uninfected hematopoietic (CD34+) cells in AIDS patients. | lld:pubmed |
pubmed-article:1382106 | pubmed:affiliation | Institutes of Microbiology and Hematology (L and A Seragnoli), University of Bologna, Italy. | lld:pubmed |
pubmed-article:1382106 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1382106 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:1382106 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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