| pubmed-article:1370178 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1370178 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:1370178 | lifeskim:mentions | umls-concept:C0374711 | lld:lifeskim |
| pubmed-article:1370178 | lifeskim:mentions | umls-concept:C0007303 | lld:lifeskim |
| pubmed-article:1370178 | lifeskim:mentions | umls-concept:C0043240 | lld:lifeskim |
| pubmed-article:1370178 | lifeskim:mentions | umls-concept:C0027758 | lld:lifeskim |
| pubmed-article:1370178 | lifeskim:mentions | umls-concept:C0031437 | lld:lifeskim |
| pubmed-article:1370178 | lifeskim:mentions | umls-concept:C1705181 | lld:lifeskim |
| pubmed-article:1370178 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1370178 | pubmed:dateCreated | 1992-1-30 | lld:pubmed |
| pubmed-article:1370178 | pubmed:abstractText | The healing of articular surface defects has been studied with conventional histology, which relies on the staining of the extracellular matrix to identify the phenotype of the cells present. A chondrospecific cellular marker would be useful. S-100 protein has been found in all chondroid tissues studied, and we evaluated its usefulness in the study of articular cartilage repair. Full-thickness rabbit femoral condylar defects were made, and the specimens were studied at serial time intervals. S-100 protein staining positively showed chondroid cells in the 7- and 14-day specimens, which were not identifiable by conventional techniques. At 30 and 60 days, an S-100 positive band of cells separated a deep safranin-O positive hypertrophic layer from a fibrocellular surface layer. At 120 days, the presence of S-100 protein identified cells with chondrogenic potential, and the lack of S-100 protein in other cells embedded in conventionally stained matrix suggested that these cells were no longer of a chondroid phenotype. The presence of S-100 protein-identified chondroid cells early in the repair process when the cells had not begun to synthesize conventionally stainable matrix and the lack of S-100 protein in cells late in the repair positively identified a phenotypic change earlier than conventional histology. | lld:pubmed |
| pubmed-article:1370178 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1370178 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1370178 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1370178 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1370178 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1370178 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1370178 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1370178 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:1370178 | pubmed:issn | 0736-0266 | lld:pubmed |
| pubmed-article:1370178 | pubmed:author | pubmed-author:WolffD ADA | lld:pubmed |
| pubmed-article:1370178 | pubmed:author | pubmed-author:GoldbergV MVM | lld:pubmed |
| pubmed-article:1370178 | pubmed:author | pubmed-author:StevensonSS | lld:pubmed |
| pubmed-article:1370178 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1370178 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:1370178 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1370178 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1370178 | pubmed:pagination | 49-57 | lld:pubmed |
| pubmed-article:1370178 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:meshHeading | pubmed-meshheading:1370178-... | lld:pubmed |
| pubmed-article:1370178 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1370178 | pubmed:articleTitle | S-100 protein immunostaining identifies cells expressing a chondrocytic phenotype during articular cartilage repair. | lld:pubmed |
| pubmed-article:1370178 | pubmed:affiliation | Department of Orthopaedics, Case Western Reserve University, Cleveland, Ohio. | lld:pubmed |
| pubmed-article:1370178 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1370178 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1370178 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1370178 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1370178 | lld:pubmed |
