| pubmed-article:1359838 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:1359838 | lifeskim:mentions | umls-concept:C0317588 | lld:lifeskim |
| pubmed-article:1359838 | lifeskim:mentions | umls-concept:C0004793 | lld:lifeskim |
| pubmed-article:1359838 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:1359838 | lifeskim:mentions | umls-concept:C0017801 | lld:lifeskim |
| pubmed-article:1359838 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:1359838 | pubmed:dateCreated | 1992-12-23 | lld:pubmed |
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| pubmed-article:1359838 | pubmed:abstractText | A 3.3-kb BamHI fragment of Lactobacillus delbrueckii subsp. bulgaricus DNA was cloned and sequenced. It complements an Escherichia coli glnA deletion strain and hybridizes strongly to a DNA containing the Bacillus subtilis glnA gene. DNA sequence analysis of the L. delbrueckii subsp. bulgaricus DNA showed it to contain the glnA gene encoding class I glutamine synthetase, as judged by extensive homology with other prokaryotic glnA genes. The sequence suggests that the enzyme encoded in this gene is not controlled by adenylylation. Based on a comparison of glutamine synthetase sequences, L. delbrueckii subsp. bulgaricus is much closer to gram-positive eubacteria, especially Clostridium acetobutylicum, than to gram-negative eubacteria and archaebacteria. The fragment contains another open reading frame encoding a protein of unknown function consisting of 306 amino acids (ORF306), which is also present upstream of glnA of Bacillus cereus. In B. cereus, a repressor gene, glnR, is found between the open reading frame and glnA. Two proteins encoded by the L. delbrueckii subsp. bulgaricus gene were identified by the maxicell method; the sizes of these proteins are consistent with those of the open reading frames of ORF306 and glnA. The lack of a glnR gene in the L. delbrueckii subsp. bulgaricus DNA in this position may indicate a gene rearrangement or a different mechanism of glnA gene expression. | lld:pubmed |
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| pubmed-article:1359838 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1359838 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1359838 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1359838 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1359838 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1359838 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1359838 | pubmed:issn | 0099-2240 | lld:pubmed |
| pubmed-article:1359838 | pubmed:author | pubmed-author:SöllDD | lld:pubmed |
| pubmed-article:1359838 | pubmed:author | pubmed-author:HottingerHH | lld:pubmed |
| pubmed-article:1359838 | pubmed:author | pubmed-author:IshinoYY | lld:pubmed |
| pubmed-article:1359838 | pubmed:author | pubmed-author:MorgenthalerP... | lld:pubmed |
| pubmed-article:1359838 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1359838 | pubmed:volume | 58 | lld:pubmed |
| pubmed-article:1359838 | pubmed:geneSymbol | glnR | lld:pubmed |
| pubmed-article:1359838 | pubmed:geneSymbol | glnA | lld:pubmed |
| pubmed-article:1359838 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1359838 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1359838 | pubmed:pagination | 3165-9 | lld:pubmed |
| pubmed-article:1359838 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
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| pubmed-article:1359838 | pubmed:meshHeading | pubmed-meshheading:1359838-... | lld:pubmed |
| pubmed-article:1359838 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1359838 | pubmed:articleTitle | Organization and nucleotide sequence of the glutamine synthetase (glnA) gene from Lactobacillus delbrueckii subsp. bulgaricus. | lld:pubmed |
| pubmed-article:1359838 | pubmed:affiliation | Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511. | lld:pubmed |
| pubmed-article:1359838 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1359838 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1359838 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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