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pubmed-article:1336194pubmed:abstractTextWe have studied by the in situ hybridization method the presence of Epstein-Barr virus (EBV) DNA genome in lymph node tissues from 11 patients with persistent generalized lymphadenopathy. Using a biotinylated EBV DNA probe, we demonstrated EBV nucleic acid in scattered germinal centre cells in eight of the 11 cases. Our results suggest that EBV is not a determinant factor in the pathogenesis of this lymphadenopathy, but support its possible implication in B cell malignant transformation in cases of AIDS-associated lymphoma.lld:pubmed
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pubmed-article:1336194pubmed:articleTitleIn situ demonstration of Epstein-Barr virus in intravenous drug abusers with generalized lymphadenopathy.lld:pubmed
pubmed-article:1336194pubmed:affiliationDepartment of Pathology, Hospital Ramon y Cajal, Madrid, Spain.lld:pubmed
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