| pubmed-article:1325391 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1325391 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:1325391 | lifeskim:mentions | umls-concept:C0040132 | lld:lifeskim |
| pubmed-article:1325391 | lifeskim:mentions | umls-concept:C0521447 | lld:lifeskim |
| pubmed-article:1325391 | lifeskim:mentions | umls-concept:C0010531 | lld:lifeskim |
| pubmed-article:1325391 | lifeskim:mentions | umls-concept:C0033634 | lld:lifeskim |
| pubmed-article:1325391 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:1325391 | pubmed:dateCreated | 1992-10-7 | lld:pubmed |
| pubmed-article:1325391 | pubmed:abstractText | Ras proteins are membrane-associated transducers of eternal stimuli to unknown intracellular targets. The constitutively activated v-ras oncogene induces dedifferentiation in thyroid cells. v-Ras appears to act by stimulating protein kinase C (PKC), which inhibits the nuclear migration of the catalytic subunit of the cAMP-dependent protein kinase A (PKA). Nuclear tissue-specific and housekeeping trans-acting factors that are dependent on phosphorylation by PKA are thus inactivated. Exclusion of the PKA subunit from the nucleus could represent a general mechanism for the pleiotropic effects of Ras and PKC on cellular growth and differentiation. | lld:pubmed |
| pubmed-article:1325391 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1325391 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1325391 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1325391 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1325391 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1325391 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1325391 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1325391 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1325391 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1325391 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1325391 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:GarbeGG | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:GalloAA | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:GottesmanM... | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:CassanoSS | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:MustiA MAM | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:AvvedimentoE... | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:BenusiglioEE | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:BonapaceI MIM | lld:pubmed |
| pubmed-article:1325391 | pubmed:author | pubmed-author:FelicielloAA | lld:pubmed |
| pubmed-article:1325391 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1325391 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:1325391 | pubmed:geneSymbol | v-ras | lld:pubmed |
| pubmed-article:1325391 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1325391 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1325391 | pubmed:pagination | 1621-30 | lld:pubmed |
| pubmed-article:1325391 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:1325391 | pubmed:meshHeading | pubmed-meshheading:1325391-... | lld:pubmed |
| pubmed-article:1325391 | pubmed:meshHeading | pubmed-meshheading:1325391-... | lld:pubmed |
| pubmed-article:1325391 | pubmed:meshHeading | pubmed-meshheading:1325391-... | lld:pubmed |
| pubmed-article:1325391 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1325391 | pubmed:articleTitle | v-ras and protein kinase C dedifferentiate thyroid cells by down-regulating nuclear cAMP-dependent protein kinase A. | lld:pubmed |
| pubmed-article:1325391 | pubmed:affiliation | Dipartimento di Biologia e Patologia Molecolare e Cellulare, Universita di Napoli, Italy. | lld:pubmed |
| pubmed-article:1325391 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1325391 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1325391 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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