pubmed-article:1316740 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C0026029 | lld:lifeskim |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C1882598 | lld:lifeskim |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C0001473 | lld:lifeskim |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C0006632 | lld:lifeskim |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C0038738 | lld:lifeskim |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C1545588 | lld:lifeskim |
pubmed-article:1316740 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
pubmed-article:1316740 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:1316740 | pubmed:dateCreated | 1992-6-16 | lld:pubmed |
pubmed-article:1316740 | pubmed:abstractText | Cadmium (Cd) inhibited the activities of Na(+)-K+ ATPase (IC50 = 5.0 x 10(-5) M), K(+)-p-nitrophenyl phosphatase (PNPPase) (IC50 = 4.0 x 10(-5) M) and 3H-ouabain binding (IC50 = 7.5 x 10(-5) M) in rat brain microsomes. Monothiols (cysteine but not glutathione and D-penicillamine) and dithiols (dimercaprol, dimercaptosuccinic acid and dithiothreitol) offered varied levels of protection against Cd-inhibition of Na(+)-K+ ATPase. Protection of Na(+)-K+ ATPase by these sulfhydryl (SH) agents was higher at 7.5 as compared to 8.5 pH. The present data suggest that Cd-inhibited Na(+)-K+ ATPase, by interfering with phosphorylation of enzyme molecule and dephosphorylation of the enzyme-phosphoryl complex and exerts a similar effect to that of SH-blocking agents. | lld:pubmed |
pubmed-article:1316740 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1316740 | pubmed:language | eng | lld:pubmed |
pubmed-article:1316740 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1316740 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1316740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1316740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1316740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1316740 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1316740 | pubmed:month | May | lld:pubmed |
pubmed-article:1316740 | pubmed:issn | 0090-4341 | lld:pubmed |
pubmed-article:1316740 | pubmed:author | pubmed-author:CooperAA | lld:pubmed |
pubmed-article:1316740 | pubmed:author | pubmed-author:McNeilCC | lld:pubmed |
pubmed-article:1316740 | pubmed:author | pubmed-author:RajannaBB | lld:pubmed |
pubmed-article:1316740 | pubmed:author | pubmed-author:ChettyC SCS | lld:pubmed |
pubmed-article:1316740 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1316740 | pubmed:volume | 22 | lld:pubmed |
pubmed-article:1316740 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1316740 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1316740 | pubmed:pagination | 456-8 | lld:pubmed |
pubmed-article:1316740 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:meshHeading | pubmed-meshheading:1316740-... | lld:pubmed |
pubmed-article:1316740 | pubmed:year | 1992 | lld:pubmed |
pubmed-article:1316740 | pubmed:articleTitle | The effects of cadmium in vitro on adenosine triphosphatase system and protection by thiol reagents in rat brain microsomes. | lld:pubmed |
pubmed-article:1316740 | pubmed:affiliation | Division of Natural Sciences, Selma University, Alabama 36701. | lld:pubmed |
pubmed-article:1316740 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1316740 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:1316740 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |