| pubmed-article:1314718 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1314718 | lifeskim:mentions | umls-concept:C0026140 | lld:lifeskim |
| pubmed-article:1314718 | lifeskim:mentions | umls-concept:C0377512 | lld:lifeskim |
| pubmed-article:1314718 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:1314718 | pubmed:dateCreated | 1992-5-28 | lld:pubmed |
| pubmed-article:1314718 | pubmed:abstractText | We measured the concentration of endogenous digitalis-like factors (EDLFs) in milk or colostrum of women during nursing on different days after delivery. EDLF concentrations were assayed by a solid-phase RIA involving antidigoxin antibodies and by a radioreceptor assay (RRA) involving human placenta Na+/K(+)-ATPase. The mean (SD) EDLF concentrations as measured by RIA were 35.6 (19.4) ng of digoxin equivalents per liter in milk samples (n = 37) and 61.3 (12.5) ng/L in colostrum samples (n = 5); the mean EDLF concentration as measured by RRA in milk samples (n = 11) was 573 (717) ng/L (range 0-2098). EDLF concentration in milk is greater than circulating concentrations in healthy adults but is comparable with serum concentration in the third trimester of pregnancy. In milk and serum samples (n = 8) collected at the same time, heating and (or) extracting with Sep-Pak C18 cartridges before the RIA produced significantly different EDLF values from those in untreated serum (P less than 0.001) and milk (P = 0.035). EDLF in milk appeared to be not bound or weakly bound to milk protein, as indicated by the fact that boiling did not increase the digoxin-like immunoreactivity. | lld:pubmed |
| pubmed-article:1314718 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1314718 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1314718 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1314718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1314718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1314718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1314718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1314718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1314718 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1314718 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1314718 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1314718 | pubmed:issn | 0009-9147 | lld:pubmed |
| pubmed-article:1314718 | pubmed:author | pubmed-author:ClericiGG | lld:pubmed |
| pubmed-article:1314718 | pubmed:author | pubmed-author:PaciAA | lld:pubmed |
| pubmed-article:1314718 | pubmed:author | pubmed-author:Del ChiccaM... | lld:pubmed |
| pubmed-article:1314718 | pubmed:author | pubmed-author:GiampietroOO | lld:pubmed |
| pubmed-article:1314718 | pubmed:author | pubmed-author:BiverPP | lld:pubmed |
| pubmed-article:1314718 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1314718 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:1314718 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1314718 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1314718 | pubmed:pagination | 504-6 | lld:pubmed |
| pubmed-article:1314718 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:meshHeading | pubmed-meshheading:1314718-... | lld:pubmed |
| pubmed-article:1314718 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1314718 | pubmed:articleTitle | Endogenous digitalis-like factors in human milk. | lld:pubmed |
| pubmed-article:1314718 | pubmed:affiliation | Istituto di Fisiologia Clinica del CNR, Pisa, Italy. | lld:pubmed |
| pubmed-article:1314718 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1314718 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
