pubmed-article:1298526 | pubmed:abstractText | Since 1986, 710 patients with freckles were hospitalized, and the effects of face peeling were studied. Before treatment, blood and urine routines and hepatic and renal function tests were performed in every patient. Comparisons have been made between the hepatic and renal functions before and after treatment in 100 patients. ECG was performed in all the patients before treatment, and 20 of them have been monitored continuously with ECG after treatment. Comparison of 24h urinary phenol excretion before and after treatment were made in 27 patients. In 5 patients it was showed that the amount of urine phenol declined rapidly with the time. The treatment was effective in 100% of the patients. The cure rate was 84.2%. We concluded that the treatment is an effective and safe method for ephelides in healthy persons. | lld:pubmed |