pubmed-article:12967477 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12967477 | lifeskim:mentions | umls-concept:C0033755 | lld:lifeskim |
pubmed-article:12967477 | lifeskim:mentions | umls-concept:C0024299 | lld:lifeskim |
pubmed-article:12967477 | lifeskim:mentions | umls-concept:C0086661 | lld:lifeskim |
pubmed-article:12967477 | lifeskim:mentions | umls-concept:C0205145 | lld:lifeskim |
pubmed-article:12967477 | lifeskim:mentions | umls-concept:C1158478 | lld:lifeskim |
pubmed-article:12967477 | lifeskim:mentions | umls-concept:C1705422 | lld:lifeskim |
pubmed-article:12967477 | lifeskim:mentions | umls-concept:C0205214 | lld:lifeskim |
pubmed-article:12967477 | pubmed:issue | 9 | lld:pubmed |
pubmed-article:12967477 | pubmed:dateCreated | 2003-9-11 | lld:pubmed |
pubmed-article:12967477 | pubmed:abstractText | Spontaneous pre-B lymphomas in SL/Kh mice occur by somatic acquisition of a provirus genome of endogenous murine leukemia virus (MuLV). Inverse PCR amplification and sequence analyses of a provirus and its host flanking fragment revealed a proviral insertion into c-myc in 3 out of 60 SL/Kh pre-B lymphomas, named Svi3 lymphomas (SL/Kh virus integration site-3). Southern blot analysis revealed that two lymphomas had clonal integration in c-myc exon 1 and the other, in the promoter region. In 2 out of 3 Svi3 lymphomas, a fusion transcript of provirus 3' long terminal repeat and c-myc and a normal full-length c-myc transcript were obtained, but in one Svi3 lymphoma, only the normal transcript was obtained. All three Svi3 lymphomas had increased c-myc expression, producing normal 67-kDa c-Myc protein. Svi3 lymphomas had more mature phenotypes in the steps of early B-cell differentiation than Svi1 lymphomas, in which c-myc expression was indirectly up-regulated by provirus integration into Stat5a. | lld:pubmed |
pubmed-article:12967477 | pubmed:language | eng | lld:pubmed |
pubmed-article:12967477 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12967477 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12967477 | pubmed:month | Sep | lld:pubmed |
pubmed-article:12967477 | pubmed:issn | 1347-9032 | lld:pubmed |
pubmed-article:12967477 | pubmed:author | pubmed-author:HiaiHiroshiH | lld:pubmed |
pubmed-article:12967477 | pubmed:author | pubmed-author:YamadaYoshihi... | lld:pubmed |
pubmed-article:12967477 | pubmed:author | pubmed-author:TsuruyamaTats... | lld:pubmed |
pubmed-article:12967477 | pubmed:author | pubmed-author:JinGuangG | lld:pubmed |
pubmed-article:12967477 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12967477 | pubmed:volume | 94 | lld:pubmed |
pubmed-article:12967477 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12967477 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12967477 | pubmed:pagination | 791-5 | lld:pubmed |
pubmed-article:12967477 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:meshHeading | pubmed-meshheading:12967477... | lld:pubmed |
pubmed-article:12967477 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12967477 | pubmed:articleTitle | Svi3: A provirus common integration site in c-myc in SL/Kh pre-B lymphomas. | lld:pubmed |
pubmed-article:12967477 | pubmed:affiliation | Department of Pathology and Biology of Diseases, Kyoto University Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan. | lld:pubmed |
pubmed-article:12967477 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12967477 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
entrez-gene:17869 | entrezgene:pubmed | pubmed-article:12967477 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:12967477 | lld:entrezgene |