pubmed-article:12956442 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0460148 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0086045 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0034845 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0302583 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C1268086 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0449438 | lld:lifeskim |
pubmed-article:12956442 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
pubmed-article:12956442 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:12956442 | pubmed:dateCreated | 2003-9-5 | lld:pubmed |
pubmed-article:12956442 | pubmed:abstractText | This study investigated the associations between serum transferrin receptor (sTfR) concentrations and erythropoietic activities during 3 stages of iron deficiency in humans. Serum iron markers, fluorescent intensity of reticulocytes, and sTfR concentrations were measured in 227 prepubescent children, age 9 to 12 yr. Reticulocyte subpopulations were analyzed by flow cytometry and sTfR concentrations were measured by enzyme immunoassay. Mean values of middle-fluorescence reticulocytes (MFR), reticulocyte maturity index (RMI), and sTfR concentrations were significantly higher in iron-deficiency anemia subjects than in healthy controls. Reticulocyte subpopulations increased gradually, as body iron status diminished; the mean values of MFR and RMI in subjects with serum ferritin concentrations < 4.0 microg/L were 3-fold higher than those in healthy controls (p < 0.01). Correlation coefficients of MFR and RMI vs log ferritin values (r = 0.43 and r = 0.42) were higher than those of MFR and RMI vs sTfR concentrations (r = 0.24 and r = 0.27) in iron-deficiency anemia subjects. In summary, iron deficiency leads to increased production of immature reticulocytes. Erythropoietic activity is more closely associated with log ferritin values than with sTfR concentrations in iron-deficiency anemia. | lld:pubmed |
pubmed-article:12956442 | pubmed:language | eng | lld:pubmed |
pubmed-article:12956442 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12956442 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:12956442 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12956442 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12956442 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12956442 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12956442 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12956442 | pubmed:issn | 0091-7370 | lld:pubmed |
pubmed-article:12956442 | pubmed:author | pubmed-author:PaiSoo HwanSH | lld:pubmed |
pubmed-article:12956442 | pubmed:author | pubmed-author:ChoiJong... | lld:pubmed |
pubmed-article:12956442 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12956442 | pubmed:volume | 33 | lld:pubmed |
pubmed-article:12956442 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12956442 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12956442 | pubmed:pagination | 279-84 | lld:pubmed |
pubmed-article:12956442 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:12956442 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12956442 | pubmed:articleTitle | Associations between serum transferrin receptor concentrations and erythropoietic activities according to body iron status. | lld:pubmed |
pubmed-article:12956442 | pubmed:affiliation | Department of Laboratory Medicine, College of Medicine, Inha University, Inchon, South Korea. jwchoi@inha.ac.kr | lld:pubmed |
pubmed-article:12956442 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12956442 | lld:pubmed |