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pubmed-article:12947140pubmed:abstractTextAirway inflammation may affect the decrease in lung function that occurs in response to cigarette smoke, and is an important pathological feature in chronic obstructive pulmonary disease (COPD). Group specific component (GC) can act as an inflammatory mediator and may therefore have important influences on the inflammatory reaction in the airway. Several reports have described associations between GC haplotypes and COPD but these remain controversial. In addition, most of these studies were based on a small number of subjects.lld:pubmed
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pubmed-article:12947140pubmed:articleTitleLack of association of group specific component haplotypes with lung function in smokers.lld:pubmed
pubmed-article:12947140pubmed:affiliationUniversity of British Columbia, McDonald Research Laboratories/iCAPTURE Center, St Paul's Hospital, 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6.lld:pubmed
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