| pubmed-article:1283010 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C0205527 | lld:lifeskim |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C0038585 | lld:lifeskim |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C0079883 | lld:lifeskim |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:1283010 | lifeskim:mentions | umls-concept:C0016566 | lld:lifeskim |
| pubmed-article:1283010 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1283010 | pubmed:dateCreated | 1993-2-12 | lld:pubmed |
| pubmed-article:1283010 | pubmed:abstractText | The effects of intrathecal administration of substance P and N-methyl-D-aspartate (NMDA) were studied in the formalin test in mice. Both substances were administered 5 min before injection of formalin into the hind paw. Co-administration of substance P and NMDA intensified the response in both the 1st (0-10 min) and the 2nd phase (20-30 min) of the formalin test, and increased the duration of the response. The increase in the response to formalin depended on the formalin concentration and was significant with 1% and 5% concentrations of formalin but not with a 0.05% concentration. No increase in the response was observed when NMDA or substance P was given alone. These findings indicate that concurrent activation of spinal NMDA and substance P receptors induces an enhancement of spinal transmission of nociception, and that this enhancement is dependent on the intensity or the quality of the peripheral stimulus. | lld:pubmed |
| pubmed-article:1283010 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1283010 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1283010 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1283010 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1283010 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1283010 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1283010 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1283010 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1283010 | pubmed:issn | 0304-3959 | lld:pubmed |
| pubmed-article:1283010 | pubmed:author | pubmed-author:LundAA | lld:pubmed |
| pubmed-article:1283010 | pubmed:author | pubmed-author:HoltDD | lld:pubmed |
| pubmed-article:1283010 | pubmed:author | pubmed-author:BergeO GOG | lld:pubmed |
| pubmed-article:1283010 | pubmed:author | pubmed-author:Mjellem-JolyN... | lld:pubmed |
| pubmed-article:1283010 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1283010 | pubmed:volume | 51 | lld:pubmed |
| pubmed-article:1283010 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1283010 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1283010 | pubmed:pagination | 195-8 | lld:pubmed |
| pubmed-article:1283010 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:meshHeading | pubmed-meshheading:1283010-... | lld:pubmed |
| pubmed-article:1283010 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1283010 | pubmed:articleTitle | Intrathecal co-administration of substance P and NMDA augments nociceptive responses in the formalin test. | lld:pubmed |
| pubmed-article:1283010 | pubmed:affiliation | Department of Physiology, University of Bergen, Norway. | lld:pubmed |
| pubmed-article:1283010 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1283010 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1283010 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1283010 | lld:pubmed |
