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pubmed-article:12782763pubmed:abstractTextMonitoring treated patients with thyroid cancer for recurrent or metastatic disease is currently based upon the serial measurement of circulating plasma thyroglobulin (Tg) concentrations. However, the clinical usefulness of Tg immunoassays is limited by poor sensitivity and interference from anti-Tg antibodies. This study investigated whether the detection of Tg mRNA in peripheral blood, using reverse transcriptase polymerase chain reaction (RT-PCR), is of value in the biochemical surveillance of patients with thyroid cancer.lld:pubmed
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pubmed-article:12782763pubmed:articleTitleMeasurement of thyroglobulin mRNA in peripheral blood as an adjunctive test for monitoring thyroid cancer.lld:pubmed
pubmed-article:12782763pubmed:affiliationMolecular Medicine Research Centre, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK. dgrammatopoulos@bio.warwick.ac.uklld:pubmed
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pubmed-article:12782763pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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