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pubmed-article:12762693pubmed:dateCreated2003-5-23lld:pubmed
pubmed-article:12762693pubmed:abstractText[reaction: see text] A novel sequential glycosylation procedure is described that combines the use of 1-hydroxyl and thiodonors. The Ph(2)SO/Tf(2)O-mediated dehydrative condensation of 1-hydroxyl donors with thioglycosides affords in good yield the thiodisaccharides, which in turn can be activated by the same activator system to furnish trisaccharides. The alpha-Gal epitope and a hyaluronan trisaccharide were efficiently assembled in a one-pot procedure.lld:pubmed
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pubmed-article:12762693pubmed:pagination1947-50lld:pubmed
pubmed-article:12762693pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:12762693pubmed:year2003lld:pubmed
pubmed-article:12762693pubmed:articleTitleSequential one-pot glycosylations using 1-hydroxyl and 1-thiodonors.lld:pubmed
pubmed-article:12762693pubmed:affiliationLeiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands.lld:pubmed
pubmed-article:12762693pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:12762693pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed