pubmed-article:12655108 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:12655108 | lifeskim:mentions | umls-concept:C0036457 | lld:lifeskim |
pubmed-article:12655108 | lifeskim:mentions | umls-concept:C1513380 | lld:lifeskim |
pubmed-article:12655108 | lifeskim:mentions | umls-concept:C0022277 | lld:lifeskim |
pubmed-article:12655108 | pubmed:issue | Pt 4 | lld:pubmed |
pubmed-article:12655108 | pubmed:dateCreated | 2003-3-25 | lld:pubmed |
pubmed-article:12655108 | pubmed:abstractText | An accidental intra- and interspecies transmission of scrapie occurred in Italy in 1997 and 1998 following exposure to a vaccine against Mycoplasma agalactiae. PrP(Sc) in affected sheep and goats, collected from a single flock exposed to vaccination 2 years earlier, was molecularly typed. In five animals with iatrogenic scrapie, a PrP(Sc) type with a 20 kDa core fragment was found in all areas of the brain investigated. In three sheep and one goat, this isoform co-occurred with a fully glycosylated isoform that had a protease-resistant backbone of 17 kDa, whereas in two sheep and four goats, the two PrP(Sc) types were detected in different regions of the brain. In sheep with natural field scrapie, a PrP(Sc) type with physico-chemical properties indistinguishable from the 20 kDa isoform was found. The present results suggest the co-presence of two prion strains in mammary gland and brain homogenates used for vaccination. | lld:pubmed |
pubmed-article:12655108 | pubmed:language | eng | lld:pubmed |
pubmed-article:12655108 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12655108 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:12655108 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:12655108 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:12655108 | pubmed:month | Apr | lld:pubmed |
pubmed-article:12655108 | pubmed:issn | 0022-1317 | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:FarinazzoAles... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:ZanussoGianlu... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:MonacoSalvato... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:ForloniGianlu... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:CaramelliMari... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:SyMan SunMS | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:GelatiMatteoM | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:FioriniMichel... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:CasaloneCrist... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:AcutisPierlui... | lld:pubmed |
pubmed-article:12655108 | pubmed:author | pubmed-author:BozzettaElena... | lld:pubmed |
pubmed-article:12655108 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:12655108 | pubmed:volume | 84 | lld:pubmed |
pubmed-article:12655108 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:12655108 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:12655108 | pubmed:pagination | 1047-52 | lld:pubmed |
pubmed-article:12655108 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
pubmed-article:12655108 | pubmed:meshHeading | pubmed-meshheading:12655108... | lld:pubmed |
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pubmed-article:12655108 | pubmed:meshHeading | pubmed-meshheading:12655108... | lld:pubmed |
pubmed-article:12655108 | pubmed:meshHeading | pubmed-meshheading:12655108... | lld:pubmed |
pubmed-article:12655108 | pubmed:meshHeading | pubmed-meshheading:12655108... | lld:pubmed |
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pubmed-article:12655108 | pubmed:meshHeading | pubmed-meshheading:12655108... | lld:pubmed |
pubmed-article:12655108 | pubmed:meshHeading | pubmed-meshheading:12655108... | lld:pubmed |
pubmed-article:12655108 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:12655108 | pubmed:articleTitle | Molecular analysis of iatrogenic scrapie in Italy. | lld:pubmed |
pubmed-article:12655108 | pubmed:affiliation | Department of Neurological and Visual Sciences, University of Verona, Piazzale L. A. Scuro, 10, 37134 Verona, Italy. | lld:pubmed |
pubmed-article:12655108 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:12655108 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:12655108 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12655108 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12655108 | lld:pubmed |